Evidence map›Paper›PMID 38659936›Full record

ArticleResearch square2024

Activation of lysosomal iron triggers ferroptosis in cancer.

Raphaël Rodriguez, Tatiana Cañeque, Leeroy Baron, Sebastian Müller, Alanis Carmona, Ludovic Colombeau, Antoine Versini, Marie Sabatier, Julio Sampaio, Eikan Mishima and 24 more

Open access · greenAbstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 11 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

34 authors at 9 institutions in 3 countries.

Raphaël RodriguezInstitut Curie, CNRS.ORCID 0000-0001-7668-446X
Tatiana CañequeInstitut Curie.ORCID 0000-0002-1110-0643
Leeroy BaronInstitut Curie.
Sebastian MüllerInstitut Curie, CNRS, INSERM, PSL Research University, Equipe Labellisée Ligue Contre le Cancer.ORCID 0000-0002-3423-5364
Alanis CarmonaHarvard T. H. Chan School of Public Health.
Ludovic ColombeauInstitut Curie.
Antoine VersiniInstitut Curie.ORCID 0000-0001-9799-2701
Marie SabatierHarvard T. H. Chan School of Public Health.ORCID 0000-0001-7673-4842
Julio SampaioInstitut Curie.
Eikan MishimaInstitute of Metabolism and Cell Death, Molecular Targets & Therapeutics Center, Helmholtz Munich, Neuherberg, Germany.ORCID 0000-0002-3706-2745
Armel Picard-BernesInstitut Curie.
Stéphanie SolierInstitut Curie.
Jiashuo ZhengHelmholtz Zentrum München.
Bettina PronethHelmholtz Munich.ORCID 0000-0002-4119-9437
Leishemba ThoidingjamInstitut Curie.
Christine GailletInstitut Curie.ORCID 0000-0002-1208-1130
Laurence GrimaudENS.
Cameron FraserHarvard University.ORCID 0000-0002-8180-5913
Krystina SzyloHarvard T. H. Chan School of Public Health.
Caroline BonnetInserm.
Emmanuelle CharafeInserm.
Christophe GinestierInserm.
Patricia SantofimiaInserm.
Nelson DusettiCentre de Recherche en Cancérologie de Marseille, CRCM, Inserm, CNRS, Institut Paoli-Calmettes, Aix-Marseille Université, Marseille, France.ORCID 0000-0002-6161-8483
Juan IovannaCentre de Recherche en cancerelogie de Marseille.ORCID 0000-0003-1822-2237
Antonio Sa CunhaAPHP.ORCID 0000-0003-4015-5368
Gabriella PittauAPHP.
Pascal HammelAPHP.
Dimitri TzanisInstitut Curie.
Sylvie BonvalotInstitut Curie.
Sarah WatsonInsitut Curie.ORCID 0000-0003-4534-8783
Brent StockwellColumbia University Irving Medical Center.ORCID 0000-0002-3532-3868
Marcus ConradInstitute of Metabolism and Cell Death, Molecular Targets & Therapeutics Center, Helmholtz Munich, Neuherberg, Germany.ORCID 0000-0003-1140-5612
Jessalyn UbellackerHarvard T.H. Chan School of Public Health.ORCID 0000-0002-7855-9125
Institut Curie · FRInserm · FRHarvard University · USHelmholtz Zentrum München · DETarget (Germany) · DECentre de Recherche en Cancérologie de Marseille · FRCentre National de la Recherche Scientifique · FRColumbia University Irving Medical Center · USHarvard University Press · US

Funding

Training Program in Molecular MetabolismT32DK128781 · NIDDK · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Sudha B Biddinger, GOKHAN S HOTAMISLIGIL · 2021 to 2026
$1.1M
NIDDK NIH HHS T32 DK128781
6 · The paper itself

Abstract

Iron catalyses the oxidation of lipids in biological membranes and promotes a form of cell death referred to as ferroptosis

Identifiers

PMID38659936
PMCPMC11042398
OpenAlexW4394572004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.