Evidence map›Paper›PMID 38659931›Full record

ArticlebioRxiv : the preprint server for biology2024

Enteric glia regulate Paneth cell secretion and intestinal microbial ecology.

Aleksandra Prochera, Anoohya N Muppirala, Gavin A Kuziel, Salima Soualhi, Amy Shepherd, Liang Sun, Biju Issac, Harry J Rosenberg, Farah Karim, Kristina Perez and 5 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Aleksandra ProcheraDivision of Gastroenterology, Department of Pediatrics, Boston Children's Hospital and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA.
Anoohya N MuppiralaDivision of Gastroenterology, Department of Pediatrics, Boston Children's Hospital and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA.
Gavin A KuzielDivision of Gastroenterology, Department of Pediatrics, Boston Children's Hospital and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA.
Salima SoualhiDivision of Gastroenterology, Department of Pediatrics, Boston Children's Hospital and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA.
Amy ShepherdDivision of Gastroenterology, Department of Pediatrics, Boston Children's Hospital and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA.
Liang SunResearch Computing, Department of Information Technology, Boston Children's Hospital, 300 Longwood Ave, Boston, MA 02115, USA.
Biju IssacResearch Computing, Department of Information Technology, Boston Children's Hospital, 300 Longwood Ave, Boston, MA 02115, USA.
Harry J RosenbergDivision of Gastroenterology, Department of Pediatrics, Boston Children's Hospital and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA.
Farah KarimInstitute of Human Nutrition, Columbia University Irving Medical Center, New York, NY, USA.
Kristina PerezDivision of Gastroenterology, Department of Pediatrics, Boston Children's Hospital and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA.
Kyle H SmithDepartment of Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Tonora H ArchibaldDepartment of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Seth Rakoff-NahoumDivision of Gastroenterology, Department of Pediatrics, Boston Children's Hospital and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA.
Susan J HagenDepartment of Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Meenakshi RaoDivision of Gastroenterology, Department of Pediatrics, Boston Children's Hospital and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA.ORCID 0000-0002-8194-9204
Boston Children's Hospital · USBeth Israel Deaconess Medical Center · USColumbia University Irving Medical Center · US

Funding

STRUCTURE-FUNCTION RELATIONSHIPS IN THE ALIMENTARY TRACTP30DK034854 · NIDDK · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI LYNN BRY · 1986 to 2026
$32.4M
Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI SCOTT Loren POMEROY, MUSTAFA SAHIN · 2021 to 2026
$9.4M
Programmable benchtop bioreactors for scalable eco-evolutionary dynamics of the human microbiomeR01AI171100 · NIAID · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI KHALIL, AHMAD SAMIR, RAKOFF-NAHOUM, SETH · 2022 to 2025
$4.1M
Microbial reactivation of sex steroids and visceral painR01DK130836 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI Meenakshi Rao · 2022 to 2026
$2.7M
Isoform- and Sex-Specific Functions of CGRP in Gastrointestinal MotilityR01DK135707 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI Meenakshi Rao · 2023 to 2026
$2.6M
Enteric Glia, Sexual Dimorphism and GI MotilityK08DK110532 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI RAO, MEENAKSHI · 2016 to 2021
$862k
NIAID NIH HHS R01 AI171100NICHD NIH HHS P50 HD105351NIDDK NIH HHS K08 DK110532NIDDK NIH HHS P30 DK034854NIDDK NIH HHS R01 DK130836NIDDK NIH HHS R01 DK135707
6 · The paper itself

Abstract

Glial cells of the enteric nervous system (ENS) interact closely with the intestinal epithelium and secrete signals that influence epithelial cell proliferation and barrier formation

Identifiers

PMID38659931
PMCPMC11042301
OpenAlexW4394963671

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.