Evidence map›Paper›PMID 38659811›Full record

ArticlebioRxiv : the preprint server for biology2024

Polycystins recruit cargo to distinct ciliary extracellular vesicle subtypes.

Inna A Nikonorova, Elizabeth desRanleau, Katherine C Jacobs, Joshua Saul, Jonathon D Walsh, Juan Wang, Maureen M Barr

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Inna A NikonorovaDepartment of Genetics and Human Genetics Institute of New Jersey, Rutgers, The State University of New Jersey; Piscataway, New Jersey 08854, USA.
Elizabeth desRanleauDepartment of Genetics and Human Genetics Institute of New Jersey, Rutgers, The State University of New Jersey; Piscataway, New Jersey 08854, USA.
Katherine C JacobsDepartment of Genetics and Human Genetics Institute of New Jersey, Rutgers, The State University of New Jersey; Piscataway, New Jersey 08854, USA.
Joshua SaulDepartment of Genetics and Human Genetics Institute of New Jersey, Rutgers, The State University of New Jersey; Piscataway, New Jersey 08854, USA.
Jonathon D WalshDepartment of Genetics and Human Genetics Institute of New Jersey, Rutgers, The State University of New Jersey; Piscataway, New Jersey 08854, USA.
Juan WangDepartment of Genetics and Human Genetics Institute of New Jersey, Rutgers, The State University of New Jersey; Piscataway, New Jersey 08854, USA.
Maureen M BarrDepartment of Genetics and Human Genetics Institute of New Jersey, Rutgers, The State University of New Jersey; Piscataway, New Jersey 08854, USA.ORCID 0000-0003-4483-2952
Rutgers, The State University of New Jersey · US

Funding

IRACDA at Rutgers: INSPIRE Postdoctoral Training ProgramK12GM093854 · NIGMS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Detlev Boison, Gary A. Brewer · 2010 to 2026
$14.7M
Polycystins, cilia, and extracellular vesicles in C. elegansR01DK059418 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI Maureen M Barr · 2001 to 2026
$9.9M
Center for C elegans AnatomyR24OD010943 · OD · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI DAVID H. HALL, Nathan Schroeder · 2012 to 2026
$9.6M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Nephronophthisis-related ciliopathies and ciliary specializationR01DK116606 · NIDDK · RUTGERS, THE STATE UNIV OF N.J. · PI Maureen M Barr · 2018 to 2026
$3.7M
Fundamental biology of neuronal extracellular vesicles - RenewalRF1NS120745 · NINDS · RUTGERS, THE STATE UNIV OF N.J. · PI Maureen M Barr · 2021 to 2026
$3.0M
An Orbitrap Tribrid mass spectrometer and nanoflow LC system to upgrade the proteomics facility at Rutgers-New Brunswick and Robert Wood Johnson Medical SchoolS10OD025140 · OD · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI LOBEL, PETER · 2019 to 2019
$921k
Fundamental Biology of Neuronal Extracellular VesiclesR01NS120745 · NINDS · RUTGERS, THE STATE UNIV OF N.J. · PI BARR, MAUREEN M · 2024 to 2025
$785k
A Mass Spectrometry System for Quantitative ProteomicsS10OD016400 · OD · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI LOBEL, PETER · 2014 to 2014
$561k
NIDDK NIH HHS R01 DK059418NIDDK NIH HHS R01 DK116606NIGMS NIH HHS K12 GM093854NIH HHS P40 OD010440NIH HHS R24 OD010943NIH HHS S10 OD016400NIH HHS S10 OD025140NINDS NIH HHS R01 NS120745NINDS NIH HHS RF1 NS120745
6 · The paper itself

Abstract

Therapeutic use of tiny extracellular vesicles (EVs) requires understanding cargo loading mechanisms. Here, we used a modular proximity label approach to identify EV cargo associated with the transient potential channel (TRP) polycystin PKD-2 of

Identifiers

PMID38659811
PMCPMC11042387
OpenAlexW4394934278

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.