Evidence map›Paper›PMID 38659809›Full record

ArticlebioRxiv : the preprint server for biology2024

Spatial Coding Dysfunction and Network Instability in the Aging Medial Entorhinal Cortex.

Charlotte S Herber, Karishma J B Pratt, Jeremy M Shea, Saul A Villeda, Lisa M Giocomo

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Charlotte S HerberDepartment of Neurobiology, Stanford University School of Medicine, Stanford, CA, 94305, USA.ORCID 0000-0002-6038-6799
Karishma J B PrattDepartment of Anatomy, University of California San Francisco, 513 Parnassus Avenue, Box 0452, San Francisco, CA, 94143, USA.ORCID 0000-0002-3040-4829
Jeremy M SheaDepartment of Anatomy, University of California San Francisco, 513 Parnassus Avenue, Box 0452, San Francisco, CA, 94143, USA.ORCID 0000-0003-1965-543X
Saul A VilledaDepartment of Anatomy, University of California San Francisco, 513 Parnassus Avenue, Box 0452, San Francisco, CA, 94143, USA.ORCID 0000-0002-2726-9582
Lisa M GiocomoDepartment of Neurobiology, Stanford University School of Medicine, Stanford, CA, 94305, USA.ORCID 0000-0003-0416-2528
University of California, San Francisco · USNeurosciences Institute · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007365 · NIGMS · STANFORD UNIVERSITY · PI CHUA, KATRIN F · 1985 to 2021
$33.8M
Training CoreP50DA042012 · NIDA · STANFORD UNIVERSITY · PI Maisie KY Lo · 2017 to 2026
$27.1M
Resource Core 3 - Teaching/Training/Dissemination Core (TTDC)U19NS118284 · NINDS · STANFORD UNIVERSITY · PI DEISSEROTH, KARL A., GIOCOMO, LISA · 2021 to 2025
$18.1M
Medical Scientist Training ProgramT32GM145402 · NIGMS · STANFORD UNIVERSITY · PI Katrin F. Chua · 2022 to 2026
$10.0M
PREDOCTORAL TRAINING IN DEVELOPMENTAL BIOLOGYT32HD007470 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Todd Nystul · 1994 to 2026
$7.7M
The Dynamics of Neural Representations for Distinct Spatial Contexts and Memory EpisodesR01MH126904 · NIMH · STANFORD UNIVERSITY · PI Lisa Giocomo · 2022 to 2026
$2.0M
Precise neuromodulation for encoding reward in the hippocampusR01MH130452 · NIMH · STANFORD UNIVERSITY · PI Lisa Giocomo · 2022 to 2026
$2.0M
From Molecules to Behavior: Understanding How Aging Impacts Entorhinal-based NavigationF30AG079494 · NIA · STANFORD UNIVERSITY · PI HERBER, CHARLOTTE SOPHIA · 2022 to 2024
$98k
NIA NIH HHS F30 AG079494NICHD NIH HHS T32 HD007470NIDA NIH HHS P50 DA042012NIGMS NIH HHS T32 GM007365NIGMS NIH HHS T32 GM145402NIMH NIH HHS R01 MH126904NIMH NIH HHS R01 MH130452NINDS NIH HHS U19 NS118284
6 · The paper itself

Abstract

Across species, spatial memory declines with age, possibly reflecting altered hippocampal and medial entorhinal cortex (MEC) function. However, the integrity of cellular and network-level spatial coding in aged MEC is unknown. Here, we leveraged

Indexed as

Aginggrid cellmedial entorhinal cortexspatial memorytranscriptomics

Identifiers

PMID38659809
PMCPMC11042240
OpenAlexW4394852808

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.