Evidence map›Paper›PMID 38659789›Full record

ArticlebioRxiv : the preprint server for biology2024

Interneuron FGF13 regulates seizure susceptibility via a sodium channel-independent mechanism.

Susan Lin, Aravind R Gade, Hong-Gang Wang, James E Niemeyer, Allison Galante, Isabella DiStefano, Patrick Towers, Jorge Nunez, Maiko Matsui, Theodore H Schwartz and 2 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Susan LinCardiovascular Research Institute, Weill Cornell Medicine, New York, NY.ORCID 0000-0001-9344-6594
Aravind R GadeCardiovascular Research Institute, Weill Cornell Medicine, New York, NY.
Hong-Gang WangCardiovascular Research Institute, Weill Cornell Medicine, New York, NY.
James E NiemeyerDepartment of Neurological Surgery and Brain and Mind Research Institute, Weill Cornell Medicine of Cornell University, New York Presbyterian Hospital, New York, NY.
Allison GalanteCardiovascular Research Institute, Weill Cornell Medicine, New York, NY.
Isabella DiStefanoCardiovascular Research Institute, Weill Cornell Medicine, New York, NY.
Patrick TowersCardiovascular Research Institute, Weill Cornell Medicine, New York, NY.
Jorge NunezCardiovascular Research Institute, Weill Cornell Medicine, New York, NY.
Maiko MatsuiCardiovascular Research Institute, Weill Cornell Medicine, New York, NY.
Theodore H SchwartzDepartment of Neurological Surgery and Brain and Mind Research Institute, Weill Cornell Medicine of Cornell University, New York Presbyterian Hospital, New York, NY.
Anjali M RajadhyakshaDepartment of Pediatrics, Division of Pediatric Neurology, Weill Cornell Medicine, New York, NY; Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Geoffrey S PittCardiovascular Research Institute, Weill Cornell Medicine, New York, NY.ORCID 0000-0003-2246-0289
Cornell University · USNewYork–Presbyterian Hospital · US

Funding

Circuit and Synaptic Mechanisms of Endocannabinoid-Opioid CrosstalkR01DA054368 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Francis Sang Yong Lee, Anjali M Rajadhyaksha · 2022 to 2026
$3.5M
Dynamic changes of the Nav1.5 interactome and contributions to heart failureR01HL160089 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MARX, STEVEN O, PITT, GEOFFREY S · 2021 to 2024
$2.7M
Investigating the mechanistic contribution of Cav1.2 channels in extinction of cocaine-associated memoriesR01DA053261 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Anjali M Rajadhyaksha · 2022 to 2026
$2.6M
Genetic and Environmental Influences on AddictionT32DA039080 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Teresa A Milner · 2017 to 2026
$1.4M
PHARMACOLOGIC STUDIES OF CNS PAIN MOLULATORY SYSTEMSR01DA003980 · NIDA · UNIVERSITY OF IOWA · PI PROUDFIT, HERBERT K · 1985 to 2003
$1.0M
FGF13 Control of Hippocampal Excitability in Cocaine Contextual MemoryF31DA053796 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI LIN, SUSAN · 2022 to 2024
$122k
NHLBI NIH HHS R01 HL160089NIDA NIH HHS F31 DA053796NIDA NIH HHS R01 DA003980NIDA NIH HHS R01 DA053261NIDA NIH HHS R01 DA054368NIDA NIH HHS T32 DA039080
6 · The paper itself

Abstract

Developmental and Epileptic Encephalopathies (DEEs), a class of devastating neurological disorders characterized by recurrent seizures and exacerbated by disruptions to excitatory/inhibitory balance in the brain, are commonly caused by mutations in ion channels. Disruption of, or variants in,

Identifiers

PMID38659789
PMCPMC11042350
OpenAlexW4394933159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.