Evidence map›Paper›PMID 38659619›Full record

ArticleJournal of osteoporosis2024

Changes in Testing and Treatment Methods in Osteoporosis Care.

Takashi Nagai, Koji Ishikawa, Koki Tsuchiya, Soji Tani, Yusuke Dodo, Yusuke Oshita, Keizo Sakamoto, Nobuyuki Kawate, Yoshifumi Kudo

Abstract read
In one paragraph

Article in Journal of osteoporosis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Takashi NagaiDepartment of Rehabilitation Medicine, Showa University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0002-8815-1182
Koji IshikawaDepartment of Orthopaedic Surgery, Showa University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0003-3689-5662
Koki TsuchiyaDepartment of Orthopaedic Surgery, Showa University School of Medicine, Tokyo, Japan.
Soji TaniDepartment of Orthopaedic Surgery, Showa University School of Medicine, Tokyo, Japan.
Yusuke DodoDepartment of Orthopaedic Surgery, Showa University School of Medicine, Tokyo, Japan.
Yusuke OshitaDepartment of Orthopaedic, Showa University Northern Yokohama Hospital, Kanagawa, Yokohama, Japan.
Keizo SakamotoDepartment of Orthopaedic Surgery, Showa University School of Medicine, Tokyo, Japan.
Nobuyuki KawateDepartment of Rehabilitation Medicine, Showa University School of Medicine, Tokyo, Japan.
Yoshifumi KudoDepartment of Orthopaedic Surgery, Showa University School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoporosis treatment plays a crucial role in preventing fractures, particularly in bedridden patients. We conducted a questionnaire survey presenting hypothetical clinical cases in 2015 and 2020 to investigate trends over a 5-year period. The target population included physicians working in clinics and hospitals within our neighbourhood. The cases were presented, and the questionnaire was administered in a confidential format. The orthopaedic surgeons were matched for age and practice, resulting in 74 cases being included in the analysis. Comparing the 2015 and 2020 results, we observed a notable increase in physicians who would perform "bone mineral density measurements of the lumbar spine and hip." Furthermore, there was a significant rise in the percentage of respondents willing to test for bone metabolic markers, such as serum type I collagen cross-linked N-telopeptide (NTX), procollagen I N-terminal propeptide (P1NP), and tartrate-resistant acid phosphatase 5b (TRACP-5b). Regarding therapeutic agents, bisphosphonates decreased in usage, whereas parathyroid hormone and romosozumab witnessed an increase. In conclusion, the percentage of physicians requesting bone mineral density measurements of the lumbar spine and hip increased over the five-year period. In addition, more physicians chose to utilise bone metabolic markers due to their ease of measurement through blood tests and reduced diurnal variation. Finally, there was a marked trend towards the administration of drugs capable of rapidly and effectively increasing bone mineral density at an early stage of treatment.

Identifiers

PMID38659619
PMCPMC11042906

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.