Evidence map›Paper›PMID 38659067›Full record

ArticleJournal of medical case reports2024

Optic neuritis and mydriasis after vaccination: a case report.

Elcio Luiz Bonamigo, Pamela Kuyava, Taísa Sacomori Paula Zanotto Reginatto, Arthur Gabriel Duran, Luisa Truculo, Eglas Emanuel Rossi, Ricardo Alexandre Stock, Claudia Elisa Grasel

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Elcio Luiz BonamigoUniversity of West Santa Catarina, Street Getúlio Vargas, 2125, Neighborhood Flor da Serra, Street 13 de Maio, 314, Room 21, Joaçaba, Santa Catarina, 89600-000, Brazil. elcio.bonamigo@unoesc.edu.br.ORCID http://orcid.org/0000-0002-0226-7070
Pamela KuyavaUniversity of West Santa Catarina, Street Getúlio Vargas, 2125, Neighborhood Flor da Serra, Street 13 de Maio, 314, Room 21, Joaçaba, Santa Catarina, 89600-000, Brazil.
Taísa Sacomori Paula Zanotto ReginattoUniversity of West Santa Catarina, Street Getúlio Vargas, 2125, Neighborhood Flor da Serra, Street 13 de Maio, 314, Room 21, Joaçaba, Santa Catarina, 89600-000, Brazil.
Arthur Gabriel DuranUniversity of West Santa Catarina, Street Getúlio Vargas, 2125, Neighborhood Flor da Serra, Street 13 de Maio, 314, Room 21, Joaçaba, Santa Catarina, 89600-000, Brazil.
Luisa TruculoUniversity of West Santa Catarina, Street Getúlio Vargas, 2125, Neighborhood Flor da Serra, Street 13 de Maio, 314, Room 21, Joaçaba, Santa Catarina, 89600-000, Brazil.
Eglas Emanuel RossiUnochapecó. Street Senador Atílio Fontana, 591-E, Neighborhood Efapi, Chapecó, Santa Catarina, 89600-000, Brazil.
Ricardo Alexandre StockUniversity of West Santa Catarina, Street Getúlio Vargas, 2125, Neighborhood Flor da Serra, Street 13 de Maio, 314, Room 21, Joaçaba, Santa Catarina, 89600-000, Brazil.
Claudia Elisa GraselUniversity of West Santa Catarina, Street Getúlio Vargas, 2125, Neighborhood Flor da Serra, Street 13 de Maio, 314, Room 21, Joaçaba, Santa Catarina, 89600-000, Brazil.
Universidade do Oeste de Santa Catarina · BRCommunity University of Chapecó Region - Unochapecó · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOptic neuritis (ON) is an inflammatory demyelinating condition of the optic nerve, with various causes. Its incidence is higher in children and young adults than in older adults of both genders, but is more common in women than in men. ON is rarely associated with mydriasis, and it is seldom triggered by vaccines against tetanus and diphtheria. CASE REPORT: A 36-year-old Caucasian woman presented with bilateral ON that had started 18 days after administration of a booster dose of the double adult vaccine (dT) against diphtheria and tetanus. Bilateral mydriasis persisted after treatment and clinical resolution of the ON. She experienced severe headache, blurred vision, decreased visual acuity in the right eye and bilateral mydriasis, a diagnosis confirmed by imaging tests. Treatment with oral corticosteroids resulted in rapid resolution of the neuritis; however, mydriasis persisted for several months.

conclusionThis study describes a very unusual case of bilateral ON associated with prolonged mydriasis after vaccination against tetanus and diphtheria that regressed after treatment with oral corticosteroids. Prolonged mydriasis was the manifestation that differed from the other cases previously described.

Indexed as

MydriasisOptic NeuritisAdultDiphtheria-Tetanus VaccineFemaleHumansTreatment OutcomeVaccinationDiphtheria-Tetanus VaccineAdverse effectsCase reportMydriasisOptic neuritisVaccines

Identifiers

PMID38659067
PMCPMC11044450
OpenAlexW4395462283

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.