ArticleBMC pulmonary medicine2024
Native-lung complications following single-lung transplantation for interstitial lung disease: an in-depth analysis.
Article in BMC pulmonary medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 3 citations in OpenAlex.
- Lung transplant outcomes in recipients waitlisted for both single and double lung transplantation.JHLT open · 2026Article
- Article
- Native lung aspergilloma after single lung transplantation-a case series.Journal of thoracic disease · 2025Article
- Influence of HLA mismatch between donors and recipients on postoperative outcomes in cadaveric lung transplantation.General thoracic and cardiovascular surgery · 2025Article
- Lung transplantation for interstitial lung disease.Breathe (Sheffield, England) · 2025Review
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundInterstitial lung disease (ILD) represents a heterogeneous group of lung disorders characterized by fibrotic lung tissue changes. In regions with severe donor shortages, single-lung transplantation (SLTx) is often preferred over bilateral lung transplantation for advanced ILD. However, temporal changes and complications in the retained native lung remain poorly understood.
methodsA retrospective analysis of 149 recipients who had undergone SLTx was conducted, including 34 ILD SLTx recipients. Native-lung volume, radiological alterations, and perfusion were assessed at distinct post-SLTx time points. Statistical analyses compared ILD and non-ILD SLTx groups.
resultsOur study revealed a progressive reduction in native-lung volume over time, accompanied by radiographic deterioration and declining perfusion. Complications in the retained native lung were observed, such as pneumothorax (29.4%), pulmonary aspergillosis (11.8%), and acute exacerbation (8.9%). Long-term survival rates were similar between ILD and non-ILD SLTx recipients.
conclusionsThis study illuminates the unique challenges and complications with respect to the native lung following SLTx for ILD. Ongoing monitoring and tailored management are essential. Despite limitations, this research contributes to our understanding of the temporal progression of native-lung complications post-SLTx for ILD, underscoring the need for further investigation.
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