ReviewMolecular psychiatry2024
How does the macroenvironment influence brain and behaviour-a review of current status and future perspectives.
Review in Molecular psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impacts of extreme temperatures on mood disorders: A systematic review.European psychiatry : the journal of the Association of European Psychiatrists · 2025Pooled it
- Big data and psychiatry: advances, constraints and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- The Therapeutic Home Environment for Chronic Diseases: A Transdisciplinary Ecosystem for Achieving Migraine Freedom and Managing Comorbid Anxiety, Insomnia, and Chronic Pain.Healthcare (Basel, Switzerland) · 2026Article
- Individual differences in adolescent cortical development are associated with neighborhood characteristics: Longitudinal findings from the ABCD study.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Neurobiophilia.Brain sciences · 2026Review
- Transdiagnostic prevention in youth mental health, Part I: rationale, shared risk factors.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- The relationship between air pollution and police officers' mental health: an empirical analysis based on spatial econometric models.Scientific reports · 2025Article
- Global, regional, and national burden of mental disorders among adolescents and young adults, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.Translational psychiatry · 2025Article
- The Impact of Early Life Exposure to Air Pollution on the Brain: A Diffusion MRI Study in 10-13-Year-Old Children With and Without ADHD Diagnosis.Human brain mapping · 2025Article
- Urban mental health: a position paper of the European psychiatric association.European psychiatry : the journal of the Association of European Psychiatrists · 2025Review
- Ethnic Identity Profiles Among Adolescents in the ABCD Study: Associations with Resting State Functional Connectivity and Perceived Discrimination.bioRxiv : the preprint server for biology · 2025Article
- Sex-specific Effects of Outdoor Air Pollution on Subcortical Microstructure and Weight Gain: Findings from the ABCD StudybioRxiv : the preprint server for biology · 2025Article
- Personal brain and Spatiotemporal Psychopathology - Intrinsic vs. extrinsic sources of interindividual variability.Molecular psychiatry · 2025Article
- The interplay between physical exercise and autophagy signaling in brain health, neurodegenerative diseases and aging.Frontiers in aging neuroscience · 2025Review
- The role of interleukin-37 and interleukin-38 in the development and remission of autism spectrum disorder: a comprehensive review of neuroinflammatory mechanisms and potential therapeutic implications.Frontiers in immunology · 2025Review
- Trends and associated factors of mental health diagnoses in Catalan Primary Care (2010-2019).European psychiatry : the journal of the Association of European Psychiatrists · 2024Article
- The impact of psychosocial adversity on brain and behaviour: an overview of existing knowledge and directions for future research.Molecular psychiatry · 2024Review
- The Necessity of Taking Culture and Context into Account When Studying the Relationship between Socioeconomic Status and Brain Development.Brain sciences · 2024Review
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6 authors.
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Abstract
The environment influences brain and mental health, both detrimentally and beneficially. Existing research has emphasised the individual psychosocial 'microenvironment'. Less attention has been paid to 'macroenvironmental' challenges, including climate change, pollution, urbanicity, and socioeconomic disparity. Notably, the implications of climate and pollution on brain and mental health have only recently gained prominence. With the advent of large-scale big-data cohorts and an increasingly dense mapping of macroenvironmental parameters, we are now in a position to characterise the relation between macroenvironment, brain, and behaviour across different geographic and cultural locations globally. This review synthesises findings from recent epidemiological and neuroimaging studies, aiming to provide a comprehensive overview of the existing evidence between the macroenvironment and the structure and functions of the brain, with a particular emphasis on its implications for mental illness. We discuss putative underlying mechanisms and address the most common exposures of the macroenvironment. Finally, we identify critical areas for future research to enhance our understanding of the aetiology of mental illness and to inform effective interventions for healthier environments and mental health promotion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.