Evidence map›Paper›PMID 38658646›Full record

ArticleNature methods2024

De novo identification of CD4

Paul M Zdinak, Nishtha Trivedi, Stephanie Grebinoski, Jessica Torrey, Eduardo Zarate Martinez, Salome Martinez, Louise Hicks, Rashi Ranjan, Venkata Krishna Kanth Makani, Mary Melissa Roland and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Nature methods, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Coincident epithelial signals restrain commensal-specific CD8αβbioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. T Cell Antigen Discovery Using Cell-Based Epitope Libraries.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  11. Article
  12. Review
  13. Review
  14. Year in review 2024.Nature methods · 2025
    Article
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Paul M ZdinakDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Nishtha Trivedi *Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Stephanie Grebinoski *Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Jessica TorreyDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Eduardo Zarate MartinezDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0001-6411-3563
Salome MartinezDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Louise HicksDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Rashi RanjanDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0002-8303-7815
Venkata Krishna Kanth MakaniDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Mary Melissa RolandDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Lyubov KubloDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Sanya ArshadDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Mark S AndersonDiabetes Center, University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-3093-4758
Dario A A VignaliDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0002-2771-5992
Alok V JoglekarDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. joglekar@pitt.edu.ORCID http://orcid.org/0000-0001-7554-7447
University of Pittsburgh · USUniversity of California, San Francisco · US

Funding

Autoimmunity and Immunopathology Training ProgramT32AI089443 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHLOMCHIK, MARK J · 2010 to 2024
$6.6M
Signaling via MHC: engineering immune cells with new capabilitiesDP2AI176138 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOGLEKAR, ALOK · 2022 to 2025
$2.3M
Identification of the cognate epitopes of autoreactive T cells in Type 1 DiabetesR03DK127447 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOGLEKAR, ALOK · 2020 to 2021
$313k
NIAID NIH HHS DP2 AI176138NIAID NIH HHS T32 AI089443NIDDK NIH HHS R03 DK127447U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID) 5T32AI089443-14U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases) 1R03DK127447-01U.S. Department of Health & Human Services | NIH | NIH Office of the Director (OD) DP2 OD033187-01
6 · The paper itself

Abstract

CD4

Indexed as

CD4-Positive T-LymphocytesEpitopes, T-LymphocyteHistocompatibility Antigens Class IIAnimalsAntigen PresentationDiabetes Mellitus, Type 1HumansMiceMice, Inbred NODPeptidesReceptors, Antigen, T-CellSingle-Cell AnalysisEpitopes, T-LymphocyteHistocompatibility Antigens Class IIPeptidesReceptors, Antigen, T-Cell

Identifiers

PMID38658646
PMCPMC11093748
OpenAlexW4395074730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.