Evidence map›Paper›PMID 38658353›Full record

ArticleThe Journal of infectious diseases2024

Quadrivalent HPV Vaccine Effectiveness Against Cervical Intraepithelial Lesion Grade 2 or Worse in Norway: A Registry-Based Study of 0.9 Million Norwegian Women.

Madleen Orumaa, Elen Johanne Lahlum, Marie Gulla, Joseph E Tota, Mari Nygård, Ståle Nygård

Open access · hybridAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. HPV Type Replacement After HPV Vaccination.Current topics in microbiology and immunology · 2026
    Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Madleen OrumaaDepartment of Research, Cancer Registry of Norway, Oslo, Norway.
Elen Johanne LahlumDepartment of Research, Cancer Registry of Norway, Oslo, Norway.
Marie GullaDepartment of Research, Cancer Registry of Norway, Oslo, Norway.
Joseph E TotaMerck & Co, Inc, Rahway, New Jersey, USA.
Mari NygårdDepartment of Research, Cancer Registry of Norway, Oslo, Norway.
Ståle NygårdDepartment of Research, Cancer Registry of Norway, Oslo, Norway.ORCID 0000-0002-5263-4748
Cancer Registry of Norway · NOMerck & Co., Inc., Rahway, NJ, USA (United States) · US

Funding

Cancer Registry of NorwayMSD Norway
6 · The paper itself

Abstract

In Norway, single-cohort vaccination with quadrivalent human papillomavirus (qHPV) vaccine targeting 12-year-old girls took place in 2009-2016. In 2020, the oldest vaccinated cohort was 23 years old and had approached the age where risk of being diagnosed with cervical intraepithelial neoplasia grade 2 or worse (CIN2+) increases rapidly. The aim of this cohort study was to assess direct qHPV vaccine effectiveness (VE) against CIN2+ among Norwegian women aged 16-30 years in 2007-2020. By using population-based health registries and individual-level data on vaccination status and potential subsequent CIN2+ incidence, we found 82% qHPV VE among women vaccinated before age 17 years.

Indexed as

Papillomavirus InfectionsRegistriesUterine Cervical DysplasiaUterine Cervical NeoplasmsAdolescentAdultCohort StudiesFemaleHuman Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18HumansIncidenceNorwayPapillomavirus VaccinesVaccinationVaccine EfficacyYoung AdultHuman Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18Papillomavirus Vaccinescervical high-grade lesionshuman papillomavirus (HPV)population-based registry dataqHPV vaccinevaccine effectiveness

Identifiers

PMID38658353
PMCPMC11646582
OpenAlexW4395466346

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.