Evidence map›Paper›PMID 38657980›Full record

ArticleSaudi medical journal2024

Enteropathy and intestinal malabsorption in patients treated with antihypertensive drugs.

Sae R Lee, Eun G Lee, Young H Cho, Eun J Park, Young-In Lee, Jung I Choi, Ryuk-Jun Kwon, Soo M Son, Sang Y Lee, Yu H Yi and 6 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi medical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Sae R LeeFrom the Department of Family Medicine and Biomedical Research Institute (S. R. Lee, E. G. Lee, Y. H. Cho, E. J. Park, Y. Lee, J. I. Choi, R. Kwon, S. M. Son, S. Y. Lee); from the Department of Family Medicine (G. L. Kim, S. H. Lee, Y. J. Ra), Pusan National University Yangsan Hospital, from the Department of Family Medicine (Y. J. Kim, J. G. Lee, Y. J. Tak, Y. H. Cho, Y. H. Yi, S.H. Lee); Department of Medical Education (S. Y. Lee), Pusan National University School of Medicine, and from the Integrated Research Institute for Natural Ingredients and Functional Foods (S. Y. Lee), Yangsan, South Korea.
Eun G LeeFrom the Department of Family Medicine and Biomedical Research Institute (S. R. Lee, E. G. Lee, Y. H. Cho, E. J. Park, Y. Lee, J. I. Choi, R. Kwon, S. M. Son, S. Y. Lee); from the Department of Family Medicine (G. L. Kim, S. H. Lee, Y. J. Ra), Pusan National University Yangsan Hospital, from the Department of Family Medicine (Y. J. Kim, J. G. Lee, Y. J. Tak, Y. H. Cho, Y. H. Yi, S.H. Lee); Department of Medical Education (S. Y. Lee), Pusan National University School of Medicine, and from the Integrated Research Institute for Natural Ingredients and Functional Foods (S. Y. Lee), Yangsan, South Korea.
Young H ChoFrom the Department of Family Medicine and Biomedical Research Institute (S. R. Lee, E. G. Lee, Y. H. Cho, E. J. Park, Y. Lee, J. I. Choi, R. Kwon, S. M. Son, S. Y. Lee); from the Department of Family Medicine (G. L. Kim, S. H. Lee, Y. J. Ra), Pusan National University Yangsan Hospital, from the Department of Family Medicine (Y. J. Kim, J. G. Lee, Y. J. Tak, Y. H. Cho, Y. H. Yi, S.H. Lee); Department of Medical Education (S. Y. Lee), Pusan National University School of Medicine, and from the Integrated Research Institute for Natural Ingredients and Functional Foods (S. Y. Lee), Yangsan, South Korea.
Eun J ParkFrom the Department of Family Medicine and Biomedical Research Institute (S. R. Lee, E. G. Lee, Y. H. Cho, E. J. Park, Y. Lee, J. I. Choi, R. Kwon, S. M. Son, S. Y. Lee); from the Department of Family Medicine (G. L. Kim, S. H. Lee, Y. J. Ra), Pusan National University Yangsan Hospital, from the Department of Family Medicine (Y. J. Kim, J. G. Lee, Y. J. Tak, Y. H. Cho, Y. H. Yi, S.H. Lee); Department of Medical Education (S. Y. Lee), Pusan National University School of Medicine, and from the Integrated Research Institute for Natural Ingredients and Functional Foods (S. Y. Lee), Yangsan, South Korea.
Young-In LeeFrom the Department of Family Medicine and Biomedical Research Institute (S. R. Lee, E. G. Lee, Y. H. Cho, E. J. Park, Y. Lee, J. I. Choi, R. Kwon, S. M. Son, S. Y. Lee); from the Department of Family Medicine (G. L. Kim, S. H. Lee, Y. J. Ra), Pusan National University Yangsan Hospital, from the Department of Family Medicine (Y. J. Kim, J. G. Lee, Y. J. Tak, Y. H. Cho, Y. H. Yi, S.H. Lee); Department of Medical Education (S. Y. Lee), Pusan National University School of Medicine, and from the Integrated Research Institute for Natural Ingredients and Functional Foods (S. Y. Lee), Yangsan, South Korea.
Jung I ChoiFrom the Department of Family Medicine and Biomedical Research Institute (S. R. Lee, E. G. Lee, Y. H. Cho, E. J. Park, Y. Lee, J. I. Choi, R. Kwon, S. M. Son, S. Y. Lee); from the Department of Family Medicine (G. L. Kim, S. H. Lee, Y. J. Ra), Pusan National University Yangsan Hospital, from the Department of Family Medicine (Y. J. Kim, J. G. Lee, Y. J. Tak, Y. H. Cho, Y. H. Yi, S.H. Lee); Department of Medical Education (S. Y. Lee), Pusan National University School of Medicine, and from the Integrated Research Institute for Natural Ingredients and Functional Foods (S. Y. Lee), Yangsan, South Korea.
Ryuk-Jun KwonFrom the Department of Family Medicine and Biomedical Research Institute (S. R. Lee, E. G. Lee, Y. H. Cho, E. J. Park, Y. Lee, J. I. Choi, R. Kwon, S. M. Son, S. Y. Lee); from the Department of Family Medicine (G. L. Kim, S. H. Lee, Y. J. Ra), Pusan National University Yangsan Hospital, from the Department of Family Medicine (Y. J. Kim, J. G. Lee, Y. J. Tak, Y. H. Cho, Y. H. Yi, S.H. Lee); Department of Medical Education (S. Y. Lee), Pusan National University School of Medicine, and from the Integrated Research Institute for Natural Ingredients and Functional Foods (S. Y. Lee), Yangsan, South Korea.
Soo M SonFrom the Department of Family Medicine and Biomedical Research Institute (S. R. Lee, E. G. Lee, Y. H. Cho, E. J. Park, Y. Lee, J. I. Choi, R. Kwon, S. M. Son, S. Y. Lee); from the Department of Family Medicine (G. L. Kim, S. H. Lee, Y. J. Ra), Pusan National University Yangsan Hospital, from the Department of Family Medicine (Y. J. Kim, J. G. Lee, Y. J. Tak, Y. H. Cho, Y. H. Yi, S.H. Lee); Department of Medical Education (S. Y. Lee), Pusan National University School of Medicine, and from the Integrated Research Institute for Natural Ingredients and Functional Foods (S. Y. Lee), Yangsan, South Korea.
Sang Y LeeFrom the Department of Family Medicine and Biomedical Research Institute (S. R. Lee, E. G. Lee, Y. H. Cho, E. J. Park, Y. Lee, J. I. Choi, R. Kwon, S. M. Son, S. Y. Lee); from the Department of Family Medicine (G. L. Kim, S. H. Lee, Y. J. Ra), Pusan National University Yangsan Hospital, from the Department of Family Medicine (Y. J. Kim, J. G. Lee, Y. J. Tak, Y. H. Cho, Y. H. Yi, S.H. Lee); Department of Medical Education (S. Y. Lee), Pusan National University School of Medicine, and from the Integrated Research Institute for Natural Ingredients and Functional Foods (S. Y. Lee), Yangsan, South Korea.ORCID https://orcid.org/0000-0002-3585-9910
Yu H YiFrom the Department of Family Medicine and Biomedical Research Institute (S. R. Lee, E. G. Lee, Y. H. Cho, E. J. Park, Y. Lee, J. I. Choi, R. Kwon, S. M. Son, S. Y. Lee); from the Department of Family Medicine (G. L. Kim, S. H. Lee, Y. J. Ra), Pusan National University Yangsan Hospital, from the Department of Family Medicine (Y. J. Kim, J. G. Lee, Y. J. Tak, Y. H. Cho, Y. H. Yi, S.H. Lee); Department of Medical Education (S. Y. Lee), Pusan National University School of Medicine, and from the Integrated Research Institute for Natural Ingredients and Functional Foods (S. Y. Lee), Yangsan, South Korea.
Gyu L KimFrom the Department of Family Medicine and Biomedical Research Institute (S. R. Lee, E. G. Lee, Y. H. Cho, E. J. Park, Y. Lee, J. I. Choi, R. Kwon, S. M. Son, S. Y. Lee); from the Department of Family Medicine (G. L. Kim, S. H. Lee, Y. J. Ra), Pusan National University Yangsan Hospital, from the Department of Family Medicine (Y. J. Kim, J. G. Lee, Y. J. Tak, Y. H. Cho, Y. H. Yi, S.H. Lee); Department of Medical Education (S. Y. Lee), Pusan National University School of Medicine, and from the Integrated Research Institute for Natural Ingredients and Functional Foods (S. Y. Lee), Yangsan, South Korea.
Yun J KimFrom the Department of Family Medicine and Biomedical Research Institute (S. R. Lee, E. G. Lee, Y. H. Cho, E. J. Park, Y. Lee, J. I. Choi, R. Kwon, S. M. Son, S. Y. Lee); from the Department of Family Medicine (G. L. Kim, S. H. Lee, Y. J. Ra), Pusan National University Yangsan Hospital, from the Department of Family Medicine (Y. J. Kim, J. G. Lee, Y. J. Tak, Y. H. Cho, Y. H. Yi, S.H. Lee); Department of Medical Education (S. Y. Lee), Pusan National University School of Medicine, and from the Integrated Research Institute for Natural Ingredients and Functional Foods (S. Y. Lee), Yangsan, South Korea.
Jeong G LeeFrom the Department of Family Medicine and Biomedical Research Institute (S. R. Lee, E. G. Lee, Y. H. Cho, E. J. Park, Y. Lee, J. I. Choi, R. Kwon, S. M. Son, S. Y. Lee); from the Department of Family Medicine (G. L. Kim, S. H. Lee, Y. J. Ra), Pusan National University Yangsan Hospital, from the Department of Family Medicine (Y. J. Kim, J. G. Lee, Y. J. Tak, Y. H. Cho, Y. H. Yi, S.H. Lee); Department of Medical Education (S. Y. Lee), Pusan National University School of Medicine, and from the Integrated Research Institute for Natural Ingredients and Functional Foods (S. Y. Lee), Yangsan, South Korea.
Young Jin TakFrom the Department of Family Medicine and Biomedical Research Institute (S. R. Lee, E. G. Lee, Y. H. Cho, E. J. Park, Y. Lee, J. I. Choi, R. Kwon, S. M. Son, S. Y. Lee); from the Department of Family Medicine (G. L. Kim, S. H. Lee, Y. J. Ra), Pusan National University Yangsan Hospital, from the Department of Family Medicine (Y. J. Kim, J. G. Lee, Y. J. Tak, Y. H. Cho, Y. H. Yi, S.H. Lee); Department of Medical Education (S. Y. Lee), Pusan National University School of Medicine, and from the Integrated Research Institute for Natural Ingredients and Functional Foods (S. Y. Lee), Yangsan, South Korea.
Seung Hun LeeFrom the Department of Family Medicine and Biomedical Research Institute (S. R. Lee, E. G. Lee, Y. H. Cho, E. J. Park, Y. Lee, J. I. Choi, R. Kwon, S. M. Son, S. Y. Lee); from the Department of Family Medicine (G. L. Kim, S. H. Lee, Y. J. Ra), Pusan National University Yangsan Hospital, from the Department of Family Medicine (Y. J. Kim, J. G. Lee, Y. J. Tak, Y. H. Cho, Y. H. Yi, S.H. Lee); Department of Medical Education (S. Y. Lee), Pusan National University School of Medicine, and from the Integrated Research Institute for Natural Ingredients and Functional Foods (S. Y. Lee), Yangsan, South Korea.
Young Jin RaFrom the Department of Family Medicine and Biomedical Research Institute (S. R. Lee, E. G. Lee, Y. H. Cho, E. J. Park, Y. Lee, J. I. Choi, R. Kwon, S. M. Son, S. Y. Lee); from the Department of Family Medicine (G. L. Kim, S. H. Lee, Y. J. Ra), Pusan National University Yangsan Hospital, from the Department of Family Medicine (Y. J. Kim, J. G. Lee, Y. J. Tak, Y. H. Cho, Y. H. Yi, S.H. Lee); Department of Medical Education (S. Y. Lee), Pusan National University School of Medicine, and from the Integrated Research Institute for Natural Ingredients and Functional Foods (S. Y. Lee), Yangsan, South Korea.
RJ Lee Group (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate differences in the incidence of enteropathy or intestinal malabsorption in patients taking angiotensin II receptor blockers (ARBs), angiotensin-converting enzyme inhibitor (ACEI), calcium channel blocker (CCB), and beta blockers (BBs) at a single center in Korea.

methodsIn this retrospective study, we utilized data from the Yangsan electronic medical records to identify 129,169 patients. These individuals were prescribed olmesartan, other ARBs, ACEI, CCB, and BBs between November 2008 and February 2021.

resultsOf the 44,775 patients, 51 (0.11%) were observed to have enteropathy or intestinal malabsorption. Compared with the ACEI group, the adjusted odds ratios (ORs) for enteropathy and intestinal malabsorption were OR=1.313 (95% confidence interval [CI]: [0.188-6.798],

conclusionIn a retrospective cohort study of patients on antihypertensive medications, no significant difference was found in the incidence of enteropathy or intestinal malabsorption when ACEI was compared to olmesartan, other ARBs, CCB, and BBs.

Indexed as

Angiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAntihypertensive AgentsCalcium Channel BlockersMalabsorption SyndromesAdrenergic beta-AntagonistsAdultAgedCohort StudiesFemaleHumansHypertensionImidazolesIncidenceIntestinal DiseasesMaleAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAntihypertensive AgentsCalcium Channel BlockersImidazolesolmesartanTetrazolesantihypertensive drugsdiarrheaenteropathyintestinalmalabsorption

Identifiers

PMID38657980
PMCPMC11147586
OpenAlexW4395077030

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.