Evidence map›Paper›PMID 38657732›Full record

ArticleContemporary clinical trials2024

A digital, coach-assisted intervention to address the psychosocial needs of young adult cancer survivors: Randomized controlled trial protocol and intervention adaptation process.

Darcey M McCready, Hannah Arem, Danielle A Duarte, Kyla Dennis, Nathan Ball, Lauren A Cafferty, Pamela S Hinds, Afrah Howlader, Carla J Berg

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05905250 (An mHealth Positive Psychology Intervention to Reduce Cancer Burden in Young Adult Cancer Survivors), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05905250 nacompletednot on this map

An mHealth Positive Psychology Intervention to Reduce Cancer Burden in Young Adult Cancer Survivors

TypeinterventionalSponsorGeorge Washington UniversityRan2024 to 2025Enrolled155ConditionsSurvivorship, Cancer, Psychological Well-BeingArmsan empirically supported protocol, further refined with evidence-based strategies, Health education
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Profiles of quality of life among US young adult cancer survivors and their associations with potential psychosocial intervention targets of hope and psychological flexibility.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Darcey M McCreadyDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, USA.
Hannah AremHealthcare Delivery Research, MedStar Health Research Institute, USA; Department of Oncology, Georgetown University, USA.
Danielle A DuarteDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, USA.
Kyla DennisDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, USA.
Nathan BallDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, USA.
Lauren A CaffertyDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, USA.
Pamela S HindsDepartment of Pediatrics, George Washington University, Children's National Hospital, USA; GW Cancer Center, George Washington University, USA.
Afrah HowladerDepartment of Health Policy and Management, Milken Institute School of Public Health, George Washington University, USA.
Carla J BergDepartment of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, USA; GW Cancer Center, George Washington University, USA. Electronic address: carlaberg@gwu.edu.

Funding

Comparison of Symptom Burden/Toxicity, Neurocognitive Change, and Functional Outcomes in Pediatric Brain Tumor Patients Treated with Proton vs. Photon Radiotherapy.R01CA249988 · NCI · BAYLOR COLLEGE OF MEDICINE · PI HINDS, PAMELA S, KAHALLEY, LISA SCHUM · 2021 to 2025
$6.8M
Scaling Social Determinants of Health Screening, Social Support and Anti-Racism Training to Reduce Inequities in Minority Cancer Survivor Health and Wellbeing in Washington, DCU01DP006639 · DP · MEDSTAR HEALTH RESEARCH INSTITUTE · PI AREM, HANNAH, PRATT-CHAPMAN, MANDI L. · 2021 to 2025
$5.0M
Recreational Marijuana Marketing and Young Adult Consumer Behavior - Administrative SupplementR01DA054751 · NIDA · GEORGE WASHINGTON UNIVERSITY · PI Carla J Berg, Patricia A Cavazos-Rehg · 2022 to 2026
$4.3M
Regulatory Impact on Vape Shops and Young Adults' Use of ENDS - Diversity SupplementR01CA215155 · NCI · GEORGE WASHINGTON UNIVERSITY · PI BERG, CARLA J · 2018 to 2022
$3.4M
Implementing a Scalable Smoke-free Home Intervention in Armenia and GeorgiaR01CA278229 · NCI · GEORGE WASHINGTON UNIVERSITY · PI Carla J Berg, MICHELLE C KEGLER · 2023 to 2026
$2.3M
Effects of State Preemption of Local Tobacco Control Legislation on Disparities in Tobacco Use, Exposure and RetailR01CA275066 · NCI · GEORGE WASHINGTON UNIVERSITY · PI Carla J Berg, Y. Tony Yang · 2023 to 2026
$2.0M
Smoke-free Air Coalitions in Georgia and Armenia: A Community Randomized TrialR01TW010664 · FIC · EMORY UNIVERSITY · PI BERG, CARLA J, KEGLER, MICHELLE C · 2017 to 2021
$1.5M
Integrating clinician, caregiver and patient prioritized quality domains for home-based pediatric hospice and palliative careR01NR020608 · NINR · CHILDREN'S HOSPITAL MED CTR OF AKRON · PI GROSSOEHME, DANIEL HUCK · 2023 to 2025
$1.3M
Emory-Georgia Clean Air Research & Education (CARE) ProgramD43ES030927 · NIEHS · EMORY UNIVERSITY · PI BERG, CARLA J, CAUDLE, WILLIAM MICHAEL · 2019 to 2025
$1.2M
Assessing IQOS Marketing Influences and Consumer Behavior in Israel: Implications for the USR01CA239178 · NCI · GEORGE WASHINGTON UNIVERSITY · PI BERG, CARLA J, LEVINE, HAGAI · 2019 to 2021
$1.2M
Armenia-US Collaboration to Address Chronic Disease via Education in Social Determinants Science (ACCESS)D43TW012456 · FIC · GEORGE WASHINGTON UNIVERSITY · PI Carla J Berg, Nino Paichadze · 2023 to 2026
$974k
Bridging the gap: Delivering Equitable Colorectal Cancer ScreeningR18HS029807 · AHRQ · MEDSTAR HEALTH RESEARCH INSTITUTE · PI AREM, HANNAH · 2023 to 2024
$970k
AHRQ HHS R18 HS029807FIC NIH HHS D43 TW012456FIC NIH HHS R01 TW010664NCCDPHP CDC HHS U01 DP006639NCI NIH HHS R01 CA215155NCI NIH HHS R01 CA239178NCI NIH HHS R01 CA249988NCI NIH HHS R01 CA275066NCI NIH HHS R01 CA278229NCI NIH HHS R21 CA261884NIDA NIH HHS R01 DA054751NIEHS NIH HHS D43 ES030927NINR NIH HHS R01 NR020608NINR NIH HHS R21 NR020374
6 · The paper itself

Abstract

backgroundGiven the increasing number of young adult cancer survivors and the impacts of cancer on various life domains, interventions addressing the psychosocial needs of young adult survivors are crucial. However, such intervention research is limited, and the existing literature has often: 1) overlooked young adult survivors' psychosocial needs; 2) targeted depression, anxiety, or fear of recurrence - rather than positive outcomes like well-being; and 3) failed to consider scalable approaches, like digital health.

methodsThis paper documents the development and refinement of an 8-week digital, coach-assisted intervention targeting hope among young adult cancer survivors (ages 18-39, within 3 years of treatment completion) and presents the protocol of the 2-arm RCT (comparing intervention vs. attention control). The intervention builds upon a 2017-2018 pilot trial (n = 56); intervention refinements were based on subsequent semi-structured interviews among young adult survivors (n = 23).

resultsThe pending trial design involves an increased sample size (n = 150) to increase power and diversified recruitment efforts (i.e., clinic-based, social media, community-based organizations, etc.) to facilitate intervention reach, accessibility, and scalability. The intervention was enhanced by integrating highly relevant theoretical and therapeutic frameworks, specifically the concept of hope and Acceptance and Commitment Therapy, as well as updating intervention delivery technology. Intervention outcomes include feasibility and acceptability at end-of-treatment and preliminary efficacy on hope (primary outcome) and quality of life measures (secondary outcomes) at end-of-treatment and 16-week follow-up.

conclusionsThis paper may facilitate discussion regarding approaches for addressing the significant psychosocial challenges faced by young adult survivors and catalyze dissemination of trial results.

trial registrationNCT05905250.

Indexed as

Cancer SurvivorsAdolescentAdultAnxietyDepressionFemaleHopeHumansMaleMentoringPsychosocial InterventionQuality of LifeRandomized Controlled Trials as TopicResearch DesignYoung AdultAcceptance and commitment therapyCancer survivorshipHealth promotionHopePositive psychologyQuality of lifeYoung adult cancer survivors

Identifiers

PMID38657732
PMCPMC11365041

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.