ArticleScience translational medicine2024
The subacromial bursa modulates tendon healing after rotator cuff injury in rats.
Article in Science translational medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
14 citing papers in PubMed, 17 citations in OpenAlex.
- The Biological Effect of Platelet-Rich Plasma on Rotator Cuff Tears: A Prospective Randomized In Vivo Study.International journal of molecular sciences · 2024Trial
- Subacromial bursitis: current evidence and future directions in injection-based therapies-A narrative review.Annals of medicine · 2026Review
- Undersurface rotator cuff repair for partial-thickness tears using the Opus knotless system: a prospective cohort of 1000 consecutive cases with a 1.4% retear rate.JSES international · 2026Article
- Round versus tape sutures with interference fit anchors perform similarly in cadaveric glenoid and greater tuberosity biomechanical testing.Archives of orthopaedic and trauma surgery · 2026Article
- Reusable Instrumentation for Arthroscopic Rotator Cuff Repair May Not Impact Clinical Outcomes.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026Article
- Mitochondrial transfer and transplantation in tendon, ligament, and enthesis repair: current evidence, mechanistic rationale, and regenerative opportunities.Frontiers in cell and developmental biology · 2026Review
- Article
- The subacromial bursa in rotator cuff injury: from pathological contributor to regenerative resource?Frontiers in bioengineering and biotechnology · 2026Review
- Lymphatic-stem cell crosstalk promotes tendon regeneration via Notch1-Srebp2-mediated cholesterol metabolism.Nature communications · 2025Article
- Removal or retention: evolving views on possible roles of the subacromial bursa in rotator cuff disease.EFORT open reviews · 2025Review
- Quantitative computed tomography analysis of bone microarchitecture is associated with rotator cuff healing.Journal of orthopaedic surgery and research · 2025Article
- Review of Preclinical and Clinical Studies Supporting the Role of Polydeoxyribonucleotide in the Treatment of Tendon Disorders.Medical science monitor : international medical journal of experimental and clinical research · 2025Review
- The Evolution of Arthroscopic Shoulder Surgery: Current Trends and Future Perspectives.Journal of clinical medicine · 2025Review
- Solid-Liquid Interface Lubricating Hydrogels for Tendon-Bone Healing.Research (Washington, D.C.) · 2025Article
Corrections and comments
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Authors and funding
16 authors at 2 institutions in 1 country.
Funding
Abstract
Rotator cuff injuries result in more than 500,000 surgeries annually in the United States, many of which fail. These surgeries typically involve repair of the injured tendon and removal of the subacromial bursa, a synovial-like tissue that sits between the rotator cuff and the acromion. The subacromial bursa has been implicated in rotator cuff pathogenesis and healing. Using proteomic profiling of bursa samples from nine patients with rotator cuff injury, we show that the bursa responds to injury in the underlying tendon. In a rat model of supraspinatus tenotomy, we evaluated the bursa's effect on the injured supraspinatus tendon, the uninjured infraspinatus tendon, and the underlying humeral head. The bursa protected the intact infraspinatus tendon adjacent to the injured supraspinatus tendon by maintaining its mechanical properties and protected the underlying humeral head by maintaining bone morphometry. The bursa promoted an inflammatory response in injured rat tendon, initiating expression of genes associated with wound healing, including
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.