Evidence map›Paper›PMID 38656992›Full record

ArticlePLOS global public health2024

Participant perspectives on incentives for TB preventative therapy adherence and reduced alcohol use: A qualitative study.

Ayesha Appa, Amanda P Miller, Robin Fatch, Allen Kekibiina, Brian Beesiga, Julian Adong, Nneka Emenyonu, Kara Marson, Monica Getahun, Moses Kamya and 6 more

Abstract read
In one paragraph

Article in PLOS global public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ayesha AppaDepartment of Medicine, University of California San Francisco, San Francisco, California, United States of America.ORCID https://orcid.org/0000-0002-4602-5954
Amanda P MillerSchool of Public Health, San Diego State University, San Diego, California, United States of America.
Robin FatchDepartment of Medicine, University of California San Francisco, San Francisco, California, United States of America.
Allen KekibiinaGlobal Health Collaborative, Mbarara University of Science and Technology, Mbarara, Uganda.
Brian BeesigaInfectious Diseases Research Collaboration (IDRC), Kampala, Uganda.ORCID https://orcid.org/0000-0001-5927-8857
Julian AdongGlobal Health Collaborative, Mbarara University of Science and Technology, Mbarara, Uganda.
Nneka EmenyonuDepartment of Medicine, University of California San Francisco, San Francisco, California, United States of America.
Kara MarsonDepartment of Medicine, University of California San Francisco, San Francisco, California, United States of America.
Monica GetahunInstitute for Global Health Sciences, University of California San Francisco, San Francisco, California, United States of America.
Moses KamyaInfectious Diseases Research Collaboration (IDRC), Kampala, Uganda.
Winnie MuyindikeGlobal Health Collaborative, Mbarara University of Science and Technology, Mbarara, Uganda.ORCID https://orcid.org/0000-0002-6694-2645
Michael McDonellDepartment of Psychiatry and Behavioral Sciences, Washington State University, Spokane, Washington, United States of America.
Harsha ThirumurthyDepartment of Medical Ethics and Health Policy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Judith A HahnDepartment of Medicine, University of California San Francisco, San Francisco, California, United States of America.
Gabriel ChamieDepartment of Medicine, University of California San Francisco, San Francisco, California, United States of America.
Carol S CamlinDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of California San Francisco, San Francisco, California, United States of America.

Funding

Alcohol Research in the Science/Practitioner ModelT32AA013525 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY, ANDREA SPADONI TOWNSEND · 2002 to 2026
$8.4M
Training in HIV Translational ResearchT32AI060530 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Diane V Havlir · 2005 to 2026
$6.4M
Postdoctoral Training in Global AIDS Prevention ResearchT32MH080634 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JESSE LAWTON CLARK, Pamina Mae Gorbach · 2007 to 2026
$6.4M
University of California, San Francisco/Kaiser Permanente Northern California Division of Research Building Interdisciplinary Research Careers in Women’s Health (BIRCWH) K12 ProgramK12AR084219 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Monica Gandhi, CYNTHIA C HARPER · 2023 to 2026
$3.1M
Interventions to reduce alcohol use and increase adherence to TB preventive therapy among HIV/TB co-infected drinkers (DIPT 1/2)U01AA026223 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAHN, JUDITH ALISSA · 2017 to 2021
$2.8M
Interventions to reduce alcohol use and increase adherence to TB preventive therapy among HIV/TB co-infected drinkers (DIPT 2/2)U01AA026221 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHAMIE, GABRIEL · 2017 to 2021
$2.7M
Training in Research Program on Alcohol Use by Persons with our at Risk for HIVK24AA022586 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAHN, JUDITH ALISSA · 2013 to 2023
$1.8M
NIAAA NIH HHS K24 AA022586NIAAA NIH HHS T32 AA013525NIAAA NIH HHS U01 AA026221NIAAA NIH HHS U01 AA026223NIAID NIH HHS T32 AI060530NIAMS NIH HHS K12 AR084219NIMH NIH HHS T32 MH080634
6 · The paper itself

Abstract

Economic incentives to promote health behavior change are highly efficacious for substance use disorders as well as increased medication adherence. Knowledge about participants' experiences with and perceptions of incentives is needed to understand their mechanisms of action and optimize future incentive-based interventions. The Drinkers' Intervention to Prevent Tuberculosis (DIPT) trial enrolled people with HIV (PWH) in Uganda with latent tuberculosis and unhealthy alcohol use in a 2x2 factorial trial that incentivized recent alcohol abstinence and isoniazid (INH) adherence on monthly urine testing while on INH preventive therapy. We interviewed 32 DIPT study participants across trial arms to explore their perspectives on this intervention. Participants described 1) satisfaction with incentives of sufficient size that allowed them to purchase items that improved their quality of life, 2) multiple ways in which incentives were motivating, from gamification of "winning" through support of pre-existing desire to improve health to suggesting variable effects of extrinsic and intrinsic motivation, and 3) finding value in learning results of increased clinical monitoring. To build effective incentive programs to support both reduced substance use and increased antimicrobial adherence, we recommend carefully selecting incentive magnitude as well as harnessing both intrinsic motivation to improve health and extrinsic reward of target behavior. In addition to these participant-described strengths, incorporating results of clinical monitoring related to the incentive program that provide participants more information about their health may also contribute to health-related empowerment.

Identifiers

PMID38656992
PMCPMC11042709

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.