ArticleBioinformatics (Oxford, England)2024
MammalMethylClock R package: software for DNA methylation-based epigenetic clocks in mammals.
Article in Bioinformatics (Oxford, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Article
- Searching for shared epigenetic clocks: evaluating ultra-conserved markers in a de novo genome assembly of the albacore tuna.GeroScience · 2026Article
- Methylomic signatures of tau and amyloid-beta in transgenic mouse models of Alzheimer's disease neuropathology.NPJ dementia · 2026Article
- Methods for analysing wildlife DNA methylation data.Conservation physiology · 2026Article
- Social bonds decrease epigenetic age in male bottlenose dolphins.Communications biology · 2025Article
- Dental Ageing Offers New Insights Into the First Epigenetic Clock for Common Dolphins (Ecology and evolution · 2025Article
- Dental aging offers new insights to the first epigenetic clock for common dolphins (bioRxiv : the preprint server for biology · 2025Article
- Designing Epigenetic Clocks for Wildlife Research.Molecular ecology resources · 2025Review
- DNA Methylation Dynamics Reflect Sex and Status Differences in Mortality Rates in a Polygynous Bat.Molecular ecology · 2025Article
- Cost-effective solutions for high-throughput enzymatic DNA methylation sequencing.PLoS genetics · 2025Article
- A torpor-like state in mice slows blood epigenetic aging and prolongs healthspan.Nature aging · 2025Article
- Enhancing epigenetic aging clocks in cetaceans: accurate age estimations in small endangered delphinids, killer whales, pilot whales, belugas, humpbacks, and bowhead whales.Scientific reports · 2025Article
- Epigenetic aging studies of pair bonding in prairie voles.Scientific reports · 2024Article
- A torpor-like state (TLS) in mice slows blood epigenetic aging and prolongs healthspan.bioRxiv : the preprint server for biology · 2024Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
motivationEpigenetic clocks are prediction methods based on DNA methylation levels in a given species or set of species. Defined as multivariate regression models, these DNA methylation-based biomarkers of age or mortality risk are useful in species conservation efforts and in preclinical studies.
resultsWe present an R package called MammalMethylClock for the construction, assessment, and application of epigenetic clocks in different mammalian species. The R package includes the utility for implementing pre-existing mammalian clocks from the Mammalian Methylation Consortium. AVAILABILITY AND IMPLEMENTATION: The source code and documentation manual for MammalMethylClock, and clock coefficient .csv files that are included within this software package, can be found on Zenodo at https://doi.org/10.5281/zenodo.10971037.
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