Evidence map›Paper›PMID 38656876›Full record

ReviewMicrobial biotechnology2024

Cold-active microbial enzymes and their biotechnological applications.

Mohammed Kuddus, Roohi, Naushin Bano, Gouse Basha Sheik, Babu Joseph, Burhan Hamid, Raveendran Sindhu, Aravind Madhavan

Abstract readReview
In one paragraph

Review in Microbial biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. A Marine Alkaline Protease fromMicroorganisms · 2026
    Article
  7. Synergistic Co-Inoculation ofMicroorganisms · 2025
    Article
  8. Biochemical features and biotechnological potential of a proteolytic extract from a psychrophilic Antarctic bacterium.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  9. Article
  10. Microbes Saving Lives and Reducing Suffering.Microbial biotechnology · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mohammed KuddusDepartment of Biochemistry, College of Medicine, University of Hail, Hail, Saudi Arabia.ORCID 0000-0001-5554-0598
RoohiProtein Research Laboratory, Department of Bioengineering, Integral University, Lucknow, India.
Naushin BanoProtein Research Laboratory, Department of Bioengineering, Integral University, Lucknow, India.
Gouse Basha SheikDepartment of Microbiology, Gesco Healthcare Pvt. Ltd., Chennai, India.
Babu JosephDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Shaqra University, Shaqra, Saudi Arabia.
Burhan HamidCenter of Research for Development, University of Kashmir, Srinagar, India.
Raveendran SindhuDepartment of Food Technology, TKM Institute of Technology, Kollam, Kerala, India.
Aravind MadhavanSchool of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Kollam, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microorganisms known as psychrophiles/psychrotrophs, which survive in cold climates, constitute majority of the biosphere on Earth. Their capability to produce cold-active enzymes along with other distinguishing characteristics allows them to survive in the cold environments. Due to the relative ease of large-scale production compared to enzymes from plants and animals, commercial uses of microbial enzyme are alluring. The ocean depths, polar, and alpine regions, which make up over 85% of the planet, are inhabited to cold ecosystems. Microbes living in these regions are important for their metabolic contribution to the ecosphere as well as for their enzymes, which may have potential industrial applications. Cold-adapted microorganisms are a possible source of cold-active enzymes that have high catalytic efficacy at low and moderate temperatures at which homologous mesophilic enzymes are not active. Cold-active enzymes can be used in a variety of biotechnological processes, including food processing, additives in the detergent and food industries, textile industry, waste-water treatment, biopulping, environmental bioremediation in cold climates, biotransformation, and molecular biology applications with great potential for energy savings. Genetically manipulated strains that are suitable for producing a particular cold-active enzyme would be crucial in a variety of industrial and biotechnological applications. The potential advantage of cold-adapted enzymes will probably lead to a greater annual market than for thermo-stable enzymes in the near future. This review includes latest updates on various microbial source of cold-active enzymes and their biotechnological applications.

Indexed as

BacteriaBiotechnologyCold TemperatureEnzymesEnzyme StabilityEnzymes

Identifiers

PMID38656876
PMCPMC11042537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.