Evidence map›Paper›PMID 38656750›Full record

ArticleEndocrine2024

1,25(OH)

Zhengyu Zhou, Lewen Zhang, Xun Wei, Aiqing Wang, Yudie Hu, Min Xiao, Yuxuan Zheng

Abstract read
PubMed Publisher
In one paragraph

Article in Endocrine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zhengyu ZhouLaboratory Animal Center of Suzhou Medical college, Soochow University, Suzhou, China. zacharyzhou@suda.edu.cn.
Lewen Zhang *Laboratory Animal Center of Suzhou Medical college, Soochow University, Suzhou, China.
Xun Wei *Center of Laboratory Animal, Shanghai Jiao Tong University, Shanghai, China.
Aiqing Wang *Suzhou Medical college of Soochow University, Suzhou, China.
Yudie HuLaboratory Animal Center of Suzhou Medical college, Soochow University, Suzhou, China.
Min XiaoLaboratory Animal Center of Suzhou Medical college, Soochow University, Suzhou, China.
Yuxuan ZhengLaboratory Animal Center of Suzhou Medical college, Soochow University, Suzhou, China.
Soochow University · CNShanghai Mental Health Center · CN

Funding

National Natural Science Foundation of China 31970505
6 · The paper itself

Abstract

purposeTo evaluate the effect and mechanism of 1,25(OH)

methodsA mouse model of T2DM was successfully established by high-fat diet (HFD) /streptozotocin (STZ) and administered 1,25(OH)

resultsPSCs activation and islets fibrosis in T2DM mice. Elevated blood glucose was accompanied by significant increases in serum inflammatory cytokines and tissue ROS levels. 1,25(OH)

conclusionOur findings identify that PSCs activation contributes to islet fibrosis and β-cell dysfunction. 1,25(OH)

Indexed as

CalcitriolDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2InsulinInsulin SecretionPancreatic Stellate CellsAnimalsBlood GlucoseCoculture TechniquesFibrosisMaleMiceMice, Inbred C57BLReactive Oxygen SpeciesBlood GlucoseCalcitriolInsulinReactive Oxygen SpeciesFibrosisInflammation.Pancreatic stellate cellsType 2 diabetes mellitusVitamin D

Identifiers

PMID38656750
OpenAlexW4395111791

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.