Evidence map›Paper›PMID 38656584›Full record

ReviewThe Journal of antimicrobial chemotherapy2024

Cardiometabolic health in people with HIV: expert consensus review.

Rachel L Batterham, Roger J Bedimo, Ricardo S Diaz, Giovanni Guaraldi, Janet Lo, Esteban Martínez, Grace A McComsey, Ana Milinkovic, Toshio Naito, Sebastian Noe and 8 more

Abstract readReviewConsensus Statement
In one paragraph

Review in The Journal of antimicrobial chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Rachel L BatterhamUCL Division of Medicine, UCL School of Life and Medical Sciences, University College London, Gower Street, London WC1E 6BT, UK.
Roger J BedimoInfectious Disease Section, VA North Texas Health Care System, 4500 S Lancaster Road, Dallas, TX 75216, USA.
Ricardo S DiazInfectious Diseases Department, Paulista School of Medicine, Federal University of São Paulo, R. Sena Madureira, 1500 Vila Clementino, São Paulo, 04021-001, Brazil.ORCID 0000-0002-8395-7304
Giovanni GuaraldiModena HIV Metabolic Clinic, University of Modena and Reggio Emilia, Via Università 4, 41121 Modena, Italy.ORCID 0000-0002-5724-3914
Janet LoDepartment of Medicine, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.ORCID 0000-0002-5678-6140
Esteban MartínezInfectious Diseases Unit, Hospital Clinic and University of Barcelona, C. de Villarroel, 170, 08036 Barcelona, Spain.ORCID 0000-0002-6911-8846
Grace A McComseyCase Center for Diabetes, Obesity and Metabolism, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA.
Ana MilinkovicGlobal Medical, ViiV Healthcare, 980 Great West Road, Brentford, Middlesex TW8 9GS, UK.
Toshio NaitoDepartment of General Medicine, Juntendo University Faculty of Medicine, 2 Chome-1-1 Hongo, Bunkyo City, Tokyo 113-8421, Japan.
Sebastian NoeMVZ Karlsplatz, MVZ Karlsplatz 8, 80335, Munich, Germany.
Donal O'SheaHealth Sciences Centre, University College Dublin School of Medicine, Belfield, Dublin 4, Ireland.
Roger ParedesDepartment of Infectious Diseases, Hospital Universitari Germans Trias i Pujol, Carretera de Canyet, s/n, 08916 Badalona, Barcelona, Spain.
Jonathan M SchapiroNational Hemophilia Center, Sheba Medical Center, Derech Sheba 2, Ramat Gan, Tel Aviv, Israel.
Mark S SulkowskiDepartment of Medicine, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD 21205, USA.
François VenterEzintsha, University of the Witwatersrand, 1 Jan Smuts Avenue, Braamfontein 2000, Johannesburg, South Africa.ORCID 0000-0002-4157-732X
Laura WatersMortimer Market Centre, Central and North West London NHS Foundation Trust, 350 Euston Road, Regent's Place, London NW1 3AX, UK.
Ilksen Ungan YorukGeneral Medicines Europe, GSK, 980 Great West Road, Brentford, Middlesex TW8 9GS, UK.
Benjamin YoungGlobal Medical, ViiV Healthcare, 406 Blackwell Street, Suite 300, Durham, NC 27701, USA.

Funding

Clinical and Translational Science Collaborative of Northern Ohio, Catalyzing Linkages to Equity in Health (CLE Health)UM1TR004528 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI GRACE A MCCOMSEY · 2023 to 2026
$32.1M
NCATS NIH HHS UM1 TR004528ViiV Healthcare
6 · The paper itself

Abstract

objectivesTo develop consensus data statements and clinical recommendations to provide guidance for improving cardiometabolic health outcomes in people with HIV based on the knowledge and experience of an international panel of experts.

methodsA targeted literature review including 281 conference presentations, peer-reviewed articles, and background references on cardiometabolic health in adults with HIV published between January 2016 and April 2022 was conducted and used to develop draft consensus data statements. Using a modified Delphi method, an international panel of 16 experts convened in workshops and completed surveys to refine consensus data statements and generate clinical recommendations.

resultsOverall, 10 data statements, five data gaps and 14 clinical recommendations achieved consensus. In the data statements, the panel describes increased risk of cardiometabolic health concerns in people with HIV compared with the general population, known risk factors, and the potential impact of antiretroviral therapy. The panel also identified data gaps to inform future research in people with HIV. Finally, in the clinical recommendations, the panel emphasizes the need for a holistic approach to comprehensive care that includes regular assessment of cardiometabolic health, access to cardiometabolic health services, counselling on potential changes in weight after initiating or switching antiretroviral therapy and encouraging a healthy lifestyle to lower cardiometabolic health risk.

conclusionsOn the basis of available data and expert consensus, an international panel developed clinical recommendations to address the increased risk of cardiometabolic disorders in people with HIV to ensure appropriate cardiometabolic health management for this population.

Indexed as

Cardiovascular DiseasesHIV InfectionsCardiometabolic Risk FactorsDelphi TechniqueHumansRisk Factors

Identifiers

PMID38656584
PMCPMC11144490

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.