ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2024
Predictive role of systemic immune-inflammation index and neutrophil/lymphocyte ratio values in infants with retinopathy of prematurity.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Significance of serum biomarkers in preterm infants screened for retinopathy of prematurity: a systematic review and meta-analysis.Eye (London, England) · 2025Pooled it
- Validation of the DIGIROP 2.0 Models in predicting the risk of treatment-requiring retinopathy of prematurity in a Taiwanese cohort.Eye (London, England) · 2026Article
- The predictive role of early and late-stage inflammatory markers in the development of retinopathy of prematurity in discordant twins.Eye (London, England) · 2026Article
- Association of Early and Late Postnatal Serum Lactate/Albumin Ratio and Retinopathy of Prematurity in Preterm Infants: A 2 Time Point Comparative Study.The Eurasian journal of medicine · 2026Article
- Corrected gestational age-specific prediction models for identifying treatment-requiring retinopathy of prematurity.Japanese journal of ophthalmology · 2026Article
- Association of vitamin D status with novel hemogram-derived inflammatory indices in preterm infants.BMC pediatrics · 2026Article
- Risk factors for severe retinopathy of prematurity: A retrospective case-control study.Experimental and therapeutic medicine · 2026Article
- Optimised multivariable prediction model to predict treatment requirement in preterm infants with retinopathy of prematurity.Eye (London, England) · 2026Article
- Predicting the treatment-requiring retinopathy of prematurity using birth weight, laboratory data and continuous peripheral capillary oxygen saturation monitoring.Japanese journal of ophthalmology · 2026Article
- Comment on: Significance of serum biomarkers in preterm infants screened for retinopathy of prematurity: a systematic review and meta-analysis.Eye (London, England) · 2026Article
- Influence of Functional Variations in Genes of Neurotrophins and Neurotransmitter Systems on the Development of Retinopathy of Prematurity.International journal of molecular sciences · 2025Article
- Beyond anti-VEGF: expanding the therapeutic horizon and biomarker landscape in retinopathy of prematurity.Frontiers in pediatrics · 2025Review
- Progress in the study of association between hematological indicators and retinopathy of prematurity (Review).Biomedical reports · 2024Review
- Lymphocyte-to-monocyte ratio as a clinical predictor in sudden sensorineural hearing loss.Brazilian journal of otorhinolaryngologyArticle
- Does First Blood Draw Matter in Retinopathy of Prematurity: A Comparative Analysis of Inflammation and Hypoxia-Related Parameters.Romanian journal of ophthalmologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo search the relationship between serum neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), and systemic immune-inflammation index (SII) values with the development of retinopathy of prematurity (ROP) and the requirement for laser treatment.
methodsThis retrospective cohort study was carried out with 195 preterm infants between 2012 and 2023. The NLR, PLR, LMR, and SII values were calculated on both the first day and at the end of the first month after birth. The association between development of ROP and other risk factors were analyzed using univariate analysis and multivariate logistic regression analysis.
resultsOf patients, 92 infants were diagnosed with ROP. Laser treatment was administered to 36 infants. The postnatal first-day NLR and SII values were higher in infants with ROP than in infants without ROP (p < 0.001 for both). Postnatal first-month NLR, LMR, and SII values were higher in infants with ROP (p < 0.001, p = 0.007, and p < 0.001, respectively). In multivariate analyses, postnatal first-day NLR and first-month LMR values were regarded as independent risk factors for the development of ROP (OR:8.867 and 1.286, p = 0.002 and p = 0.009, respectively). In multivariate analyses performed for laser treatment requirement, postnatal first-month PLR and SII values were determined as independent risk factors (OR:0.951 and 1.011, respectively, p = 0.004 for both).
conclusionsPostnatal first-day NLR and first-month LMR values were determined as independent risk factors for the development of ROP. For the requirement of laser treatment, the postnatal first-month PLR and SII values were determined as independent risk factors.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.