Evidence map›Paper›PMID 38656189›Full record

ArticleEnvironmental science & technology2024

Should Transformation Products Change the Way We Manage Chemicals?

Daniel Zahn, Hans Peter H Arp, Kathrin Fenner, Anett Georgi, Jasmin Hafner, Sarah E Hale, Juliane Hollender, Thomas Letzel, Emma L Schymanski, Gabriel Sigmund and 1 more

Abstract read
In one paragraph

Article in Environmental science & technology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  9. Article
  10. Article
  11. Article
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  13. Environmental science & technology · 2025
    Review
  14. Review
  15. Article
  16. Plant Uptake of Persistent and Mobile Chemicals in Rocket (Environmental science & technology · 2025
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Daniel ZahnHelmholtz Centre for Environmental Research - UFZ, Permoserstrasse 15, 04318 Leipzig, Germany.ORCID 0000-0003-3038-9371
Hans Peter H ArpNorwegian Geotechnical Institute (NGI), P.O. Box 3930, Ullevål Stadion, 0806 Oslo, Norway.ORCID 0000-0002-0747-8838
Kathrin FennerSwiss Federal Institute of Aquatic Science and Technology (Eawag), 8600 Dübendorf, Zürich, Switzerland.ORCID 0000-0001-6068-8220
Anett GeorgiHelmholtz Centre for Environmental Research - UFZ, Permoserstrasse 15, 04318 Leipzig, Germany.ORCID 0000-0002-2941-1255
Jasmin HafnerSwiss Federal Institute of Aquatic Science and Technology (Eawag), 8600 Dübendorf, Zürich, Switzerland.ORCID 0000-0002-1474-5869
Sarah E HaleTZW: DVGW Water Technology Center, Karlsruher Str. 84, 76139 Karlsruhe, Germany.ORCID 0000-0002-7743-9199
Juliane HollenderSwiss Federal Institute of Aquatic Science and Technology (Eawag), 8600 Dübendorf, Zürich, Switzerland.ORCID 0000-0002-4660-274X
Thomas LetzelAFIN-TS GmbH (Analytisches Forschungsinstitut für Non-Target Screening), Am Mittleren Moos 48, 86167 Augsburg, Germany.
Emma L SchymanskiLuxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 6 avenue du Swing, L-4367 Belvaux, Luxembourg.ORCID 0000-0001-6868-8145
Gabriel SigmundEnvironmental Technology, Wageningen University & Research, 6700 AA Wageningen, The Netherlands.ORCID 0000-0003-2068-0878
Thorsten ReemtsmaHelmholtz Centre for Environmental Research - UFZ, Permoserstrasse 15, 04318 Leipzig, Germany.ORCID 0000-0003-1606-0764

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When chemical pollutants enter the environment, they can undergo diverse transformation processes, forming a wide range of transformation products (TPs), some of them benign and others more harmful than their precursors. To date, the majority of TPs remain largely unrecognized and unregulated, particularly as TPs are generally not part of routine chemical risk or hazard assessment. Since many TPs formed from oxidative processes are more polar than their precursors, they may be especially relevant in the context of persistent, mobile, and toxic (PMT) and very persistent and very mobile (vPvM) substances, which are two new hazard classes that have recently been established on a European level. We highlight herein that as a result, TPs deserve more attention in research, chemicals regulation, and chemicals management. This perspective summarizes the main challenges preventing a better integration of TPs in these areas: (1) the lack of reliable high-throughput TP identification methods, (2) uncertainties in TP prediction, (3) inadequately considered TP formation during (advanced) water treatment, and (4) insufficient integration and harmonization of TPs in most regulatory frameworks. A way forward to tackle these challenges and integrate TPs into chemical management is proposed.

Indexed as

Environmental PollutantsRisk AssessmentEnvironmental Pollutantsadvanced oxidation processesemerging contaminantsnontarget screeningrisk assessmentWater management

Identifiers

PMID38656189
PMCPMC11080041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.