Evidence map›Paper›PMID 38656029›Full record

ArticleArquivos brasileiros de oftalmologia2024

Comparison of keratoplasty outcomes at the scar versus edema stages of keratoconus.

Yingxin Chen, Zhida You, Cuiyu Wang, Ruiyao Gao, Kai Zhang

Open access · diamondAbstract readComparative Study
In one paragraph

Article in Arquivos brasileiros de oftalmologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Corneal and Endothelial Parameters Following Scleral Lens Wear in Post-Keratoplasty Eyes.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Yingxin ChenDepartment of Ophthalmology, General Hospital of Northern Theater Command, Shenyang, China.ORCID 0000-0003-3470-0892
Zhida YouDepartment of Ophthalmology, General Hospital of Northern Theater Command, Shenyang, China.ORCID 0000-0002-6215-8052
Cuiyu WangDepartment of Ophthalmology, General Hospital of Northern Theater Command, Shenyang, China.ORCID 0009-0003-0432-5566
Ruiyao GaoDepartment of Ophthalmology, General Hospital of Northern Theater Command, Shenyang, China.ORCID 0009-0002-1757-0125
Kai ZhangDepartment of Ophthalmology, General Hospital of Northern Theater Command, Shenyang, China.ORCID 0009-0007-5393-1326
General Hospital of Shenyang Military Region · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the outcomes of deep anterior lamellar keratoplasty or penetrating keratoplasty at the scar and the edema stages.

methodsForty-five patients (45 eyes) with keratoconus scar stage (scar group, n=26; penetrating keratoplasty a subgroup, n=7; deep anterior lamellar keratoplasty b subgroup, n=19) and keratoconus edema stage (edema group, n=19; penetrating keratoplasty c subgroup, n=12; deep anterior lamellar keratoplasty d group, n=7) who received penetrating keratoplasty or deep anterior lamellar keratoplasty from 2000 to 2022 were retrospectively studied. At 1, 6, and 12 months after surgery, the best-corrected visual acuity, astigmatism, spherical equivalent, corneal endothelial cell density, and complications were analyzed.

resultsThe best-corrected visual acuity and average corneal endothelial cell loss rate were not significantly different between the scar and edema groups (p>0.05). At 6 and 12 months after surgery, the astigmatism and spherical equivalent in the scar group were significantly lower than those in the edema group (p<0.05). The spherical equivalent of the deep anterior lamellar keratoplasty b subgroup was lower than that of the penetrating keratoplasty a subgroup in the scar group 6 months after surgery (p<0.05). In the edema group, there was no significant difference in spherical equivalent between subgroups (p>0.05). There were no significant differences in best-corrected visual acuity and astigmatism between subgroups within the two groups (p>0.05). In comparison to the scar group, the edema group experienced more complications. According to a survival analysis, there was no statistically significant difference between the scar group and the edema group regarding the progression of vision.

conclusionsIn terms of the outcomes and prognosis for vision after keratoplasty with edema stage and scar stage, deep anterior lamellar keratoplasty may be as effective as penetrating keratoplasty.

Indexed as

CicatrixCorneal EdemaKeratoconusKeratoplasty, PenetratingVisual AcuityAdolescentAdultAstigmatismCell CountCorneal TransplantationEndothelium, CornealFemaleHumansMaleMiddle AgedPostoperative Complications

Identifiers

PMID38656029
PMCPMC11622842
OpenAlexW4393206366

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.