Evidence map›Paper›PMID 38655989›Full record

SynthesisSao Paulo medical journal = Revista paulista de medicina2024

Suicide ideation and psychotropic recreational drug use by adolescents: a systematic review and meta-analysis.

Cássia Lima de Oliveira Gracini, Gustavo Giacomelli Nascimento, Maria Tereza Campos Vidigal, Murilo Navarro de Oliveira, Álex Moreira Herval, Cauane Blumenberg, Walbert A Vieira, Rafael Rodrigues Lima, Luiz Renato Paranhos

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Sao Paulo medical journal = Revista paulista de medicina, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cássia Lima de Oliveira GraciniMSc. Nurse, Master's student, Postgraduate Program in Management and Public Health, Universidade Estadual de Campinas (UNICAMP), Piracicaba (SP), Brazil.ORCID 0000-0002-7809-4882
Gustavo Giacomelli NascimentoPhD. Dentist, Principal Investigator, National Dental Centre Singapore, National Dental Research Institute Singapore, Singapore, Singapore; Professor, Oral Health Academic Clinical Programme, Duke-NUS Medical School, Singapore, Singapore.ORCID 0000-0002-4288-6300
Maria Tereza Campos VidigalMSc. Dentist, Master's student, Postgraduate Program in Dentistry, School of Dentistry, Universidade Federal de Uberlândia (UFU), Uberlândia (MG), Brazil.ORCID 0000-0002-0508-3269
Murilo Navarro de OliveiraMSc. Dentist, Doctoral student, Postgraduate Program in Dentistry, School of Dentistry, Universidade Federal de Uberlândia (UFU), Uberlândia (MG), Brazil.ORCID 0000-0002-8555-3960
Álex Moreira HervalPhD. Dentist, Professor, Division of Preventive and Community Dentistry, School of Dentistry, Universidade Federal de Uberlândia (UFU), Uberlândia (MG), Brazil.ORCID 0000-0001-6649-2616
Cauane BlumenbergPhD. Computer Scientist, Collaborative Researcher, Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.ORCID 0000-0002-4580-3849
Walbert A VieiraMSc. Dentist, Doctoral student, Department of Restorative Dentistry, Endodontics Division, School of Dentistry of Piracicaba, Universidade Estadual de Campinas (UNICAMP), Piracicaba (SP), Brazil.ORCID 0000-0001-8872-2865
Rafael Rodrigues LimaPhD. Dentist, Professor, Laboratory of Functional and Structural Biology, Institute of Biological Sciences, Universidade Federal do Pará, Belém (PA), Brazil.ORCID 0000-0003-1486-4013
Luiz Renato ParanhosPhD. Dentist, Professor, Division of Preventive and Community Dentistry, School of Dentistry, Federal University of Uberlândia, Uberlândia, Brazil.ORCID 0000-0002-7599-0120

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdolescence is characterized by complex and dynamic changes, often involving experimentation, including the use of psychotropic substances. Although it is well-established that recreational psychotropic drugs are associated with suicide ideation in adults, evidence of this association in adolescents remains limited.

objectiveTo investigate the relationship between suicide ideation and psychotropic recreational drug use among adolescents. DESIGN AND

settingSystematic review with meta-analysis developed at Universidade Federal de Uberlândia (UFU) and Universidade Estadual de Campinas (UNICAMP), Brazil.

methodsA search across eight electronic databases for observational studies, without language or publication year restrictions, was conducted. The Joanna Briggs Institute tool was used to assess the risk of bias. Random-effects meta-analyses and odds ratios were used to measure the effects.

resultsThe search yielded 19,732 studies, of which 78 were included in the qualitative synthesis and 32 in the meta-analysis. The findings indicated that suicidal ideation was 1.96 times more likely (95% confidence interval, CI = 1.47; 2.61) for adolescents who used some drug recurrently and 3.32 times more likely (95%CI = 1.86; 5.93) among those who abused drugs. Additionally, adolescents who used cannabis were 1.57 times more likely (95%CI = 1.34; 1.84) to experience suicide ideation compared with non-users, while cocaine users had 2.57 times higher odds (95%CI = 1.47; 4.50).

conclusionsPsychotropic recreational drug use is associated with suicidal ideation among adolescents regardless of current or previous use, abuse, or type of substance used. SYSTEMATIC REVIEW REGISTRATION: Registered in the PROSPERO database under the identification number CRD42021232360. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021232360.

Indexed as

Psychotropic DrugsRecreational Drug UseSuicidal IdeationAdolescentBrazilFemaleHumansIllicit DrugsMaleRisk FactorsSubstance-Related DisordersIllicit DrugsPsychotropic Drugs

Identifiers

PMID38655989
PMCPMC11034886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.