Evidence map›Paper›PMID 38655876›Full record

ArticleRenal failure2024

Factors associated with post-hospitalization dialysis dependence in ECMO patients who required continuous renal replacement therapy.

Carlos Rodrigo Franco Palacios, Rudiona Hoxhaj, Catlyn Thigpen, Jeffrey Jacob

Open access · goldAbstract read
In one paragraph

Article in Renal failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Carlos Rodrigo Franco PalaciosCritical Care Medicine, WellStar Health System, Marietta, GA, USA.ORCID 0000-0003-3635-0654
Rudiona HoxhajInternal Medicine, WellStar Health System, Marietta, GA, USA.ORCID 0009-0002-7933-7329
Catlyn ThigpenInternal Medicine, WellStar Health System, Marietta, GA, USA.ORCID 0009-0005-7498-3796
Jeffrey JacobInternal Medicine, WellStar Health System, Marietta, GA, USA.ORCID 0009-0005-8260-3562
WellStar Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis single center retrospective study aimed to describe the variables associated with outpatient dialysis dependence in extracorporeal membrane oxygenation (ECMO) patients who needed continuous renal replacement therapy (CRRT) for acute kidney injury (AKI) during their hospitalization.

methodsRetrospective study of patients who required ECMO-CRRT.

resultsBetween the years of 2016 and 2022, 202 patients required ECMO-CRRT. One hundred and six patients (52.5%) survived their hospitalization and were followed up for a median of 391 [133, 1005] days. Eighty-one patients (76.5%) recovered kidney function and were dialysis-free before hospital discharge. Twenty-five patients (23.5%) were hemodialysis-dependent after hospitalization. On multivariate regression analysis, hyperlipidemia (odds ratio, OR 6.08 [1.67-22]) and CRRT duration (OR 1.09 [1.03-1.15]) were associated with the need for dialysis post-hospitalization. In this group, 16 patients eventually became dialysis-free, after a median of 49 [34.7, 78.5] days. These patients had a higher median baseline glomerular filtration rate (GFR) compared to those who never recovered renal function (93 mL/min/1.73 m

conclusionsAKI requiring CRRT was associated with high mortality in patients receiving ECMO. Nonetheless, most ECMO survivors became dialysis-free before hospital discharge. Variables associated with the need for outpatient dialysis included hyperlipidemia and prolonged need for CRRT during hospitalization.

Indexed as

Acute Kidney InjuryContinuous Renal Replacement TherapyExtracorporeal Membrane OxygenationGlomerular Filtration RateRenal DialysisAdultAgedFemaleHospitalizationHumansHyperlipidemiasMaleMiddle AgedPatient DischargeRetrospective StudiesRisk FactorsChronic kidney diseasecontinuous renal replacement therapydialysisextracorporeal membrane oxygenation

Identifiers

PMID38655876
PMCPMC11044754
OpenAlexW4395109433

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.