Evidence map›Paper›PMID 38655676›Full record

Trial reportHuman vaccines & immunotherapeutics2024

Lung mucosal immunity to NTHi vaccine antigens: Antibodies in sputum of chronic obstructive pulmonary disease patients.

Federica Baffetta, Cecilia Buonsanti, Luca Moraschini, Susanna Aprea, Martina Canè, Stefano Lombardi, Mario Contorni, Simona Rondini, Ashwani Kumar Arora, Monia Bardelli and 3 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Human vaccines & immunotherapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Inflammatory Responses to Non-TypeablePathogens (Basel, Switzerland) · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Federica BaffettaGSK, Siena, Italy.ORCID 0009-0009-5508-4049
Cecilia BuonsantiGSK, Siena, Italy.ORCID 0000-0001-5785-7695
Luca MoraschiniGSK, Siena, Italy.ORCID 0000-0002-3244-9043
Susanna ApreaGSK, Siena, Italy.
Martina CanèUniversity of Naples, Naples, Italy.ORCID 0009-0007-5222-323X
Stefano LombardiGSK, Siena, Italy.ORCID 0009-0000-1395-1604
Mario ContorniGSK, Siena, Italy.ORCID 0000-0001-9720-8972
Simona RondiniGSK Vaccines Institute for Global Health (GVGH), Siena, Italy.ORCID 0000-0002-5114-1511
Ashwani Kumar AroraGSK Vaccines Institute for Global Health (GVGH), Siena, Italy.ORCID 0000-0003-3694-9878
Monia BardelliGSK, Siena, Italy.ORCID 0000-0002-9722-024X
Oretta FincoGSK, Siena, Italy.ORCID 0000-0002-8652-6534
Davide SerrutoGSK, Siena, Italy.
Silvia Rossi PaccaniGSK, Siena, Italy.ORCID 0000-0003-0136-9814
Global Vaccines (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic obstructive pulmonary disease (COPD) is a common chronic respiratory illness in older adults. A major cause of COPD-related morbidity and mortality is acute exacerbation of COPD (AECOPD). Bacteria in the lungs play a role in exacerbation development, and the most common pathogen is non-typeable

Indexed as

Antibodies, BacterialAntigens, BacterialHaemophilus InfectionsHaemophilus influenzaeHaemophilus VaccinesImmunity, MucosalImmunoglobulin AImmunoglobulin GPulmonary Disease, Chronic ObstructiveSputumAgedAged, 80 and overFemaleHumansLungMaleAntibodies, BacterialAntigens, BacterialHaemophilus VaccinesImmunoglobulin AImmunoglobulin Gbacterial infectionCOPD exacerbationsCOPD pathologyinfection controlrespiratory infection

Identifiers

PMID38655676
PMCPMC11057560
OpenAlexW4395076240

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.