Evidence map›Paper›PMID 38655560›Full record

ArticleIJID regions2024

Genomic surveillance of SARS-CoV-2 in North Africa: 4 years of GISAID data sharing.

Zaineb Hamzaoui, Sana Ferjani, Ines Medini, Latifa Charaa, Ichrak Landolsi, Roua Ben Ali, Wissal Khaled, Sarra Chammam, Salma Abid, Lamia Kanzari and 7 more

Abstract read
In one paragraph

Article in IJID regions, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Zaineb HamzaouiFaculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.
Sana FerjaniFaculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.
Ines MediniNational Center Chalbibelkahia of Pharmacovigilance of Tunis, Laboratory of Clinical Pharmacology, Tunis, Tunisia.
Latifa CharaaLaboratory of Microbiology, Charles Nicolle Hospital, Tunis, Tunisia.
Ichrak LandolsiLaboratory of Microbiology, Charles Nicolle Hospital, Tunis, Tunisia.
Roua Ben AliNational Center Chalbibelkahia of Pharmacovigilance of Tunis, Laboratory of Clinical Pharmacology, Tunis, Tunisia.
Wissal KhaledLaboratory of Microbiology, Charles Nicolle Hospital, Tunis, Tunisia.
Sarra ChammamNational Center Chalbibelkahia of Pharmacovigilance of Tunis, Laboratory of Clinical Pharmacology, Tunis, Tunisia.
Salma AbidFaculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.
Lamia KanzariFaculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.
Asma FerjaniFaculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.
Ahmed FakhfakhFaculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.
Dhouha KebaierFaculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.
Zoubeir BouslahFaculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.
Mouna Ben SassiNational Center Chalbibelkahia of Pharmacovigilance of Tunis, Laboratory of Clinical Pharmacology, Tunis, Tunisia.
Sameh TrabelsiNational Center Chalbibelkahia of Pharmacovigilance of Tunis, Laboratory of Clinical Pharmacology, Tunis, Tunisia.
Ilhem Boutiba-Ben BoubakerFaculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aimed to construct geographically, temporally, and epidemiologically representative data sets for SARS-CoV-2 in North Africa, focusing on Variants of Concern (VOCs), Variants of Interest (VOIs), and Variants Under Monitoring (VUMs). Methods: SARS-CoV-2 genomic sequences and metadata from the EpiCoV database via the Global Initiative on Sharing All Influenza Data platform were analyzed. Data analysis included cases, deaths, demographics, patient status, sequencing technologies, and variant analysis. Results: A comprehensive analysis of 10,783 viral genomic sequences from six North African countries revealed notable insights. SARS-CoV-2 sampling methods lack standardization, with a majority of countries lacking clear strategies. Over 59% of analyzed genomes lack essential clinical and demographic metadata, including patient age, sex, underlying health conditions, and clinical outcomes, which are essential for comprehensive genomic analysis and epidemiological studies, as submitted to the Global Initiative on Sharing All Influenza Data. Morocco reported the highest number of confirmed COVID-19 cases (1,272,490), whereas Tunisia leads in reported deaths (29,341), emphasizing regional variations in the pandemic's impact. The GRA clade emerged as predominant in North African countries. The lineage analysis showcased a diversity of 190 lineages in Egypt, 26 in Libya, 121 in Tunisia, 90 in Algeria, 146 in Morocco, and 10 in Mauritania. The temporal dynamics of SARS-CoV-2 variants revealed distinct waves driven by different variants. Conclusions: This study contributes valuable insights into the genomic landscape of SARS-CoV-2 in North Africa, highlighting the importance of genomic surveillance in understanding viral dynamics and informing public health strategies.

Indexed as

Epidemiological dynamicsGenomic sequencesLineagesNorth AfricaSARS-CoV-2Variants

Identifiers

PMID38655560
PMCPMC11035039

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.