Evidence map›Paper›PMID 38655549›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Characterizing cognitive profiles in diverse middle-aged and older Hispanics/Latinos: Study of Latinos-Investigation of Neurocognitive Aging (HCHS/SOL).

Lisa V Graves, Wassim Tarraf, Kevin Gonzalez, Mark W Bondi, Linda C Gallo, Carmen R Isasi, Martha Daviglus, Melissa Lamar, Donglin Zeng, Jianwen Cai and 1 more

Open access · goldAbstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Heterogeneity in cognitive profiles of monolingual and bilingual Hispanic/Latino older adults in HABS-HD.Journal of the International Neuropsychological Society : JINS · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 1 country.

Lisa V GravesDepartment of Psychology California State University San Marcos San Marcos California USA.ORCID https://orcid.org/0000-0001-6861-8745
Wassim TarrafInstitute of Gerontology & Department of Healthcare Sciences Wayne State University Detroit Michigan USA.
Kevin GonzalezDepartment of Neurosciences University of California San Diego La Jolla California USA.
Mark W BondiDepartment of Psychiatry University of California San Diego School of Medicine La Jolla California USA.
Linda C GalloDepartment of Psychology San Diego State University San Diego California USA.
Carmen R IsasiDepartment of Epidemiology & Population Health Albert Einstein College of Medicine Jack and Pearl Resnick Campus Bronx New York USA.
Martha DaviglusInstitute for Minority Health Research University of Illinois at Chicago College of Medicine Chicago Illinois USA.
Melissa LamarInstitute for Minority Health Research University of Illinois at Chicago College of Medicine Chicago Illinois USA.
Donglin ZengDepartment of Biostatistics University of North Carolina Chapel Hill North Carolina USA.
Jianwen CaiDepartment of Biostatistics University of North Carolina Chapel Hill North Carolina USA.
Hector M GonzálezDepartment of Neurosciences University of California San Diego La Jolla California USA.
University of California San Diego · USUniversity of North Carolina at Chapel Hill · USAlbert Einstein College of Medicine · USCalifornia State University, San Marcos · USRush University Medical Center · USSan Diego State University · USUniversity of Illinois Chicago · USWayne State University · US

Funding

UCSD Shiley-Marcos Alzheimer's Disease Research Center P30P30AG062429 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DOUGLAS R GALASKO · 2019 to 2026
$34.9M
Study of Latinos-Investigation of Neurocognitive Aging-Alzheimer's diseaseR01AG075758 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Charles DeCarli, Hector M Gonzalez · 2022 to 2026
$21.7M
Culturally relevant contributors to cognitive and MRI changes in older LatinosR01AG062711 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LAMAR, MELISSA · 2020 to 2025
$3.6M
Thalassemia Clinical Research Network, CanadaU01HL065233 · NHLBI · UNIVERSITY HEALTH NETWORK · PI OLIVIERI, NANCY F · 2000 to 2009
$2.6M
GENETIC ARCHITECTURE OF PLASMA T-PA AND PAI-1R01HL065234 · NHLBI · VANDERBILT UNIVERSITY · PI MOORE, JASON H. · 2000 to 2004
$1.7M
Semiparametric Regression Analysis of Interval-Censored Data in Current Cohort StudiesR01HL173128 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Donglin Zeng · 2024 to 2026
$1.2M
HISPANIC COMMUNITY HEALTH STUDY-268065233N01HC065233 · HC · COORDINATING CENTER · PI CHAMBLESS, LLOYD E · 2006 to 2006
–
NHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237NHLBI NIH HHS R01 HL173128NIA NIH HHS P30 AG062429NIA NIH HHS R01 AG062711NIA NIH HHS R01 AG075758
6 · The paper itself

Abstract

Introduction: We investigated cognitive profiles among diverse, middle-aged and older Hispanic/Latino adults in the Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA) cohort using a cross-sectional observational study design. Methods: Based on weighted descriptive statistics, the average baseline age of the target population was 56.4 years, slightly more than half were women (54.6%), and 38.4% reported less than a high school education. We used latent profile analysis of demographically adjusted Results: Statistical fit assessment indices combined with clinical interpretation suggested five profiles: (1) a Higher Global group performing in the average-to-high-average range across all cognitive and instrumental activity of daily living (IADL) tests (13.8%); (2) a Higher Memory group with relatively high performance on memory tests but average performance across all other cognitive/IADL tests (24.6%); (3) a Lower Memory group with relatively low performance on memory tests but average performance across all other cognitive/IADL tests (32.8%); (4) a Lower Executive Function group with relatively low performance on executive function and processing speed tests but average-to-low-average performance across all other cognitive/IADL tests (16.6%); and (5) a Lower Global group performing low-average-to-mildly impaired across all cognitive/IADL tests (12.1%). Discussion: Our results provide evidence of heterogeneity in the cognitive profiles of a representative, community-dwelling sample of diverse Hispanic/Latino adults. Our analyses yielded cognitive profiles that may assist efforts to better understand the early cognitive changes that may portend Alzheimer's disease and related dementias among diverse Hispanics/Latinos. Highlights: The present study characterized cognitive profiles among diverse middle-aged and older Hispanic/Latino adults.Latent profile analysis of neurocognitive test scores was the primary analysis conducted.The target population consists of middle-aged and older Hispanic/Latino adults enrolled in the Hispanic Community Health Study/Study of Latinos and ancillary Study of Latinos - Investigation of Neurocognitive Aging.

Indexed as

agingAlzheimer's disease and related dementiascognitive phenotypingHispanic/Latinoneuropsychology

Identifiers

PMID38655549
PMCPMC11035970
OpenAlexW4395044751

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.