ArticleFrontiers in cardiovascular medicine2024
Chronic lead exposure and burden of cardiovascular disease during 1990-2019: a systematic analysis of the global burden of disease study.
Article in Frontiers in cardiovascular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 14 citations in OpenAlex.
- From Mass to Molecules: PMToxics · 2026Article
- Recent Advances in Aptamer-Based Applications in Cardiology.International journal of molecular sciences · 2026Review
- Global burden of cardiovascular disease attributable to lead exposure: based on the global burden of disease study 2021.Frontiers in public health · 2026Article
- Preparation, Adsorption Performance and Mechanism of Low-Cost Desert Sand-Based Pb (II) Ion-Imprinted Composites.Polymers · 2025Article
- Integrated genomic and functional analysis of a Pb-resistant Pseudomonas mendocina L1 for phytoremediation of contaminated soils.World journal of microbiology & biotechnology · 2025Article
- Assessment of water pollution and environmental impacts in the Pineios river basin before and after extreme flood events in Thessaly, Greece.Environmental science and pollution research international · 2025Article
- The Mechanisms of Lead Toxicity in Living Organisms.Journal of xenobiotics · 2025Review
- The burden and trend prediction of ischemic heart disease associated with lead exposure: Insights from the Global Burden of Disease study 2021.Environmental health : a global access science source · 2025Article
- The association between occupational lead exposure and serum levels of vitamin D3 and a bone turnover biomarker in smelter workers.International archives of occupational and environmental health · 2025Article
- Article
- Global, regional, and national burden of ischemic heart disease attributable to lead exposure, 1990-2021: decomposition, frontier, and projection analysis.Frontiers in public health · 2025Article
- Global ischemic heart disease burden attributable to environmental risk factors, 1990-2021: an Age-Period-Cohort analysis.Frontiers in public health · 2025Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Cardiovascular diseases (CVD) are the leading causes of death and disability worldwide. Lead exposure is an important risk factor for CVD. In our study, we aimed to estimate spatial and temporal trends in the burden of cardiovascular disease associated with chronic lead exposure. Methods: The data collected for our study were obtained from Global Burden of Disease (GBD) study 2019 and analyzed by age, sex, cause, and location. To assess the temporal trends in burden of CVD attributable to chronic lead exposure over 30 years, we used Joinpoint regression analysis. Results: In 2019, the number of lead exposure-attributable CVD deaths and disability-adjusted life-years (DALYs) were 0.85 and 17.73 million, 1.7 and 1.4 times more than those observed in 1990, respectively. However, the corresponding age-standardized rates (ASR) of death and DALY gradually decreased from 1990 to 2019, especially from 2013 to 2019. Over the last 30 years, among 21 GBD regions and 204 countries and territories, the High-income Asia Pacific and the Republic of Korea experienced the largest reductions in age-standardized DALY and death rates, while Central Asia and Afghanistan experienced the largest increases. Males and the elderly population suffered higher death rates and DALY burdens than females and the young population. Furthermore, we observed that higher socio-demographic index (SDI) regions demonstrated lower ASR of death and DALY rates. In 2019, the low and low-middle SDI regions, especially South Asia, exhibited the highest burden of CVD attributable to lead exposure. Conclusion: Our study provides a thorough understanding of the burden of CVD attributable to chronic lead exposure. The findings confirm the significance of implementing lead mitigation strategies and increasing investment in CVD prevention and treatment. These measures are crucial in reducing the burden of CVD and promoting public health on a global scale.
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