Evidence map›Paper›PMID 38655285›Full record

ReviewFrontiers in cellular and infection microbiology2024

Molecular mechanisms of tigecycline-resistance among

Lukasz Korczak, Piotr Majewski, Dominika Iwaniuk, Pawel Sacha, Mariola Matulewicz, Piotr Wieczorek, Paulina Majewska, Anna Wieczorek, Piotr Radziwon, Elzbieta Tryniszewska

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 37 citations in OpenAlex.

  1. Virulence · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Effect of sub-inhibitory tigecycline (½-MIC) on AcrAB-TolC andFrontiers in cellular and infection microbiology · 2026
    Article
  8. Review
  9. Antibiotic resistance inFrontiers in microbiology · 2026
    Review
  10. Whole-Genome Insights Into Tigecycline-ResistantTransboundary and emerging diseases · 2026
    Article
  11. Review
  12. Review
  13. Turning the Tide Against Carbapenem-resistantOpen forum infectious diseases · 2025
    Article
  14. Characterization of an Extensively Drug-ResistantFoods (Basel, Switzerland) · 2025
    Article
  15. Genomic Epidemiology of Vancomycin-ResistantAntibiotics (Basel, Switzerland) · 2025
    Article
  16. Molecular Epidemiology ofAntibiotics (Basel, Switzerland) · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Mobile genetic elements inJournal of bacteriology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Lukasz KorczakDepartment of Microbiological Diagnostics and Infectious Immunology, Medical University of Bialystok, Bialystok, Poland.
Piotr MajewskiDepartment of Microbiological Diagnostics and Infectious Immunology, Medical University of Bialystok, Bialystok, Poland.
Dominika IwaniukDepartment of Microbiological Diagnostics and Infectious Immunology, Medical University of Bialystok, Bialystok, Poland.
Pawel SachaDepartment of Microbiological Diagnostics and Infectious Immunology, Medical University of Bialystok, Bialystok, Poland.
Mariola MatulewiczRegional Centre for Transfusion Medicine, Bialystok, Poland.
Piotr WieczorekDepartment of Microbiological Diagnostics and Infectious Immunology, Medical University of Bialystok, Bialystok, Poland.
Paulina MajewskaRegional Centre for Transfusion Medicine, Bialystok, Poland.
Anna WieczorekDepartment of Microbiological Diagnostics and Infectious Immunology, Medical University of Bialystok, Bialystok, Poland.
Piotr RadziwonRegional Centre for Transfusion Medicine, Bialystok, Poland.
Elzbieta TryniszewskaDepartment of Microbiological Diagnostics and Infectious Immunology, Medical University of Bialystok, Bialystok, Poland.
Medical University of Białystok · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global emergence of antimicrobial resistance to multiple antibiotics has recently become a significant concern. Gram-negative bacteria, known for their ability to acquire mobile genetic elements such as plasmids, represent one of the most hazardous microorganisms. This phenomenon poses a serious threat to public health. Notably, the significance of tigecycline, a member of the antibiotic group glycylcyclines and derivative of tetracyclines has increased. Tigecycline is one of the last-resort antimicrobial drugs used to treat complicated infections caused by multidrug-resistant (MDR) bacteria, extensively drug-resistant (XDR) bacteria or even pan-drug-resistant (PDR) bacteria. The primary mechanisms of tigecycline resistance include efflux pumps' overexpression,

Indexed as

Anti-Bacterial AgentsEnterobacteriaceaeTigecyclineDrug Resistance, BacterialDrug Resistance, Multiple, BacterialEnterobacteriaceae InfectionsHumansMicrobial Sensitivity TestsMinocyclinePlasmidsAnti-Bacterial AgentsMinocyclineTigecyclineefflux pumpsEnterobacteralesglycylcyclinesmultidrug resistance (MDR)tigecycline

Identifiers

PMID38655285
PMCPMC11035753
OpenAlexW4394618771

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.