Evidence map›Paper›PMID 38654981›Full record

ReviewTaiwan journal of ophthalmology

Main issues in penetrating keratoplasty.

Jorge L Alió, Sana Niazi, Farideh Doroodgar, Jorge L Alió Del Barrio, Hassan Hashemi, Mohammad Ali Javadi

Open access · diamondAbstract readReview
In one paragraph

Review in Taiwan journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Advances in corneal transplantation.Eye (London, England) · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Jorge L AlióDivision of Ophthalmology, Universidad Miguel Hernández, Alicante, Spain.
Sana NiaziTranslational Ophthalmology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Farideh DoroodgarTranslational Ophthalmology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Jorge L Alió Del BarrioCornea, Cataract and Refractive Surgery Unit, Vissum Corporación, Alicante, Spain.
Hassan HashemiNoor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran.
Mohammad Ali JavadiOphthalmic Research Center, Labbafinezhad Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IRMiranza · ESNoor Eye Hospital · IRShahid Beheshti University of Medical Sciences · IRUniversitat de Miguel Hernández d'Elx · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review explores contemporary challenges in penetrating keratoplasty (PK), focusing on technical intricacies, technological advancements, and strategies for preventing graft rejection. A systematic literature search from January 2018 to July 2023 was conducted across PubMed, Cochrane, Web of Science, Scopus, and EMBASE. The inclusion criteria comprised studies on PK and its comparison with other corneal pathologies, with emphasis on keratoconus (KC). Two independent reviewers screened studies, extracting relevant data. The review covers PK evolution, highlighting infra-red femtosecond lasers' impact on graft shapes, minimizing astigmatism, and enhancing wound healing. Graft rejection, a primary complication, is examined, detailing risk factors and preventive measures. Preoperative considerations, diagnostic techniques for rejection, and PK in KC are discussed. Postoperative care's significance, including intraocular pressure monitoring and steroid administration, is emphasized. The paper concludes with a comprehensive approach to prevent graft rejection, involving topical and systemic medications. An outlook on evolving monoclonal antibody research is presented. As the field progresses, personalized approaches and ongoing therapeutic exploration are expected to refine strategies, enhancing PK outcomes.

Indexed as

Corneal surgerygraft rejectionkeratoplastylaserpenetratingtrephining

Identifiers

PMID38654981
PMCPMC11034681
OpenAlexW4392358142

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.