Evidence map›Paper›PMID 38654814›Full record

ArticleQatar medical journal2024

Successful medical management of a pituitary macroadenoma with features of resistant acromegaly and hyperprolactinemia using pasireotide.

Khaled Ahmed Baagar, Amna Sadiq, Adeel Ahmad Khan, Zeinab Dabbous, Zaina Rohani

Open access · diamondAbstract read
In one paragraph

Article in Qatar medical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Khaled Ahmed BaagarDiabetes and Endocrine Department, Hamad Medical Corporation, Doha, Qatar Email: kbaagar@hamad.qa.
Amna SadiqRadiology Department, Hamad Medical Corporation, Doha, Qatar.
Adeel Ahmad KhanDiabetes and Endocrine Department, Hamad Medical Corporation, Doha, Qatar Email: kbaagar@hamad.qa.
Zeinab DabbousDiabetes and Endocrine Department, Hamad Medical Corporation, Doha, Qatar Email: kbaagar@hamad.qa.
Zaina RohaniDiabetes and Endocrine Department, Hamad Medical Corporation, Doha, Qatar Email: kbaagar@hamad.qa.
Hamad Medical Corporation · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe somatostatin analog, pasireotide, is used for the treatment of acromegaly after the failure of surgery and/or first-line medical treatment. CASE PRESENTATION: A 48-year-old male reported that during a workup for obesity in his home country, hyperprolactinemia was diagnosed and a 3.5 × 3.5 cm pituitary macroadenoma was identified on pituitary MRI. He received cabergoline for 6 months; then he was lost to follow-up. He presented at our Endocrine clinic 2 years later for treatment of obesity (BMI 49.5 kg/m

conclusionsThe case suggests that pasireotide can provide marked biochemical improvement in acromegaly after the failure of both cabergoline monotherapy and cabergoline plus octreotide. This further confirms a potentially efficacious treatment regimen in treatment-resistant acromegaly with hyperprolactinemia.

Indexed as

acromegalycase reporthyperprolactinemiapasireotidepituitary macroadenoma

Identifiers

PMID38654814
PMCPMC11037097
OpenAlexW4392893989

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.