SynthesisPublic health nutrition2024
The role of vitamin D in outcomes of critical care in COVID-19 patients: evidence from an umbrella meta-analysis of interventional and observational studies.
Synthesis in Public health nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.
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The trial behind it
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Who cites it
12 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Comparative efficacy of nutritional supplements for the prevention of respiratory tract infections in children: a systematic review and network meta-analysis.BMC infectious diseases · 2026Pooled it
- Association between prenatal vitamin D supplementation and respiratory diseases in children: a systematic review and meta-analysis.BMC pediatrics · 2025Pooled it
- Effect of vitamin D supplementation on COVID-19 outcomes: an umbrella review of systematic reviews.Frontiers in nutrition · 2025Pooled it
- Association between vitamin D deficiency and clinical outcomes in critically ill patients: A retrospective cohort study.The Journal of international medical research · 2026Article
- Serial Changes in Vitamin D Status in Patients During Severe Acute Respiratory Distress Syndrome and Extracorporeal Membrane Oxygenation.Medicina (Kaunas, Lithuania) · 2025Article
- Vitamin D Status and Incidence of SARS-CoV-2 Reinfections in the Borriana COVID-19 Cohort: A Population-Based Prospective Cohort Study.Tropical medicine and infectious disease · 2025Article
- The impact of gut microbiome modulation on anthropometric indices in metabolic syndrome: an umbrella review.Annals of medicine and surgery (2012) · 2025Article
- Herbal and Dietary Supplements as Adjunctive Treatment for Mild SARS-CoV-2 Infection in Italy.Nutrients · 2025Review
- The Association Between Dietary Supplement Use and COVID-19 Symptoms.Journal of dietary supplements · 2025Article
- Hypocalcemia is associated with adverse outcomes in patients with diabetes and COVID-19.Frontiers in endocrinology · 2025Article
- Comparison of the role of vitamin D in normal organs and those affected by COVID-19.International journal of medical sciences · 2025Review
- Malnutrition and the Post-Acute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Multi-Institutional Population-Based Propensity Score-Matched Analysis.Life (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesSeveral meta-analyses have suggested the beneficial effect of vitamin D on patients infected with severe acute respiratory syndrome coronavirus-2. This umbrella meta-analysis aims to evaluate influence of vitamin D supplementation on clinical outcomes and the mortality rate of COVID-19 patients.
designPresent study was designed as an umbrella meta-analysis. The following international databases were systematically searched till March 2023: Web of Science, PubMed, Scopus, and Embase. SETTINGS: Random-effects model was employed to perform meta-analysis. Using AMSTAR critical evaluation tools, the methodological quality of the included meta-analyses was evaluated.
participantsAdult patients suffering from COVID-19 were studied.
resultsOverall, 13 meta-analyses summarising data from 4 randomised controlled trial and 9 observational studies were identified in this umbrella review. Our findings revealed that vitamin D supplementation and status significantly reduced mortality of COVID-19 [Interventional studies: (ES = 0·42; 95 % CI: 0·10, 0·75,
conclusionOverall, vitamin D status is a critical factor influencing the mortality rate, disease severity, admission to intensive care unit and being detached from mechanical ventilation. It is vital to monitor the vitamin D status in all patients with critical conditions including COVID patients.
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