Evidence map›Paper›PMID 38654048›Full record

ArticleScientific reports2024

Enhancing physical characteristics and antibacterial efficacy of chitosan through investigation of microwave-assisted chemically formulated chitosan-coated ZnO and chitosan/ZnO physical composite.

Sara A Ali, E S Ali, G Hamdy, Mona Shaban E M Badawy, Abdallah R Ismail, Inas A El-Sabbagh, Magda M El-Fass, Moataz A Elsawy

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sara A AliChemistry Department, Faculty of Science, Al-Azhar University Girls, Nasr City, Cairo, Egypt.
E S AliPolymer Laboratory, Petrochemical Department, Egyptian Petroleum Research Institute, Nasr City, 11727, Cairo, Egypt. emansaad_80@yahoo.com.
G HamdyChemistry Department, Faculty of Science, Al-Azhar University Girls, Nasr City, Cairo, Egypt.
Mona Shaban E M BadawyDepartment of Microbiology and Immunology, Faculty of Pharmacy (Girls), Al-Azhar University, Nasr City, Cairo, Egypt.
Abdallah R IsmailDepartment of Processes Design and Development, Egyptian Petroleum Research Institute (EPRI), Nasr City, 11727, Cairo, Egypt.
Inas A El-SabbaghChemistry Department, Faculty of Science, Al-Azhar University Girls, Nasr City, Cairo, Egypt.
Magda M El-FassChemistry Department, Faculty of Science, Al-Azhar University Girls, Nasr City, Cairo, Egypt.
Moataz A ElsawyPolymer Laboratory, Petrochemical Department, Egyptian Petroleum Research Institute, Nasr City, 11727, Cairo, Egypt. mo3taz_elsawy@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the creation and analysis of chitosan-zinc oxide (CS-ZnO) nanocomposites, exploring their effectiveness in inhibiting bacteria. Two synthesis approaches, physical and chemical, were utilized. The CS-ZnO nanocomposites demonstrated strong antibacterial properties, especially against Staphylococcus aureus, a Gram-positive bacterium. Chemically synthesized nanocomposites (CZ10 and CZ100) exhibited larger inhibition zones (16.4 mm and 18.7 mm) compared to physically prepared CS-Z5 and CS-Z20 (12.2 mm and 13.8 mm) against Staphylococcus aureus. Moreover, CZ nanocomposites displayed enhanced thermal stability, with decomposition temperatures of 281°C and 290°C, surpassing CS-Z5 and CS-Z20 (260°C and 258°C). The residual mass percentages at 800°C were significantly higher for CZ10 and CZ100 (58% and 61%) than for CS-Z5 and CS-Z20 (36% and 34%). UV-Visible spectroscopy revealed reduced band gaps in the CS-ZnO nanocomposites, indicating improved light absorption. Transmission electron microscopy (TEM) confirmed uniform dispersion of ZnO nanoparticles within the chitosan matrix. In conclusion, this research underscores the impressive antimicrobial potential of CS-ZnO nanocomposites, especially against Gram-positive bacteria, and highlights their enhanced thermal stability. These findings hold promise for diverse applications in industries such as medicine, pharmaceuticals, and materials science, contributing to the development of sustainable materials with robust antimicrobial properties.

Indexed as

Anti-Bacterial AgentsChitosanMicrowavesNanocompositesStaphylococcus aureusZinc OxideMicrobial Sensitivity TestsAnti-Bacterial AgentsChitosanZinc OxideAntimicrobial activityChitosanMicrowaveZinc oxide nanoparticles

Identifiers

PMID38654048
PMCPMC11039724

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.