Evidence map›Paper›PMID 38654023›Full record

ArticleNature communications2024

In situ captured antibacterial action of membrane-incising peptide lamellae.

Kamal El Battioui, Sohini Chakraborty, András Wacha, Dániel Molnár, Mayra Quemé-Peña, Imola Cs Szigyártó, Csenge Lilla Szabó, Andrea Bodor, Kata Horváti, Gergő Gyulai and 9 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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  3. Parametrization of βJournal of chemical information and modeling · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Kamal El BattiouiInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, H-1117, Hungary.
Sohini ChakrabortyInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, H-1117, Hungary.
András WachaInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, H-1117, Hungary.ORCID http://orcid.org/0000-0002-9609-0893
Dániel MolnárInstitute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest, H-1117, Hungary.
Mayra Quemé-PeñaInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, H-1117, Hungary.
Imola Cs SzigyártóInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, H-1117, Hungary.
Csenge Lilla SzabóHevesy György Ph.D. School of Chemistry, Eötvös Loránd University, Budapest, H-1117, Hungary.ORCID http://orcid.org/0000-0002-6508-3439
Andrea BodorELTE Eötvös Loránd University, Institute of Chemistry, Analytical and BioNMR Laboratory, Budapest, H-1117, Hungary.ORCID http://orcid.org/0000-0002-7422-298X
Kata HorvátiMTA-HUN-REN TTK "Momentum" Peptide-Based Vaccines Research Group, Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, Budapest, H-1117, Hungary.
Gergő GyulaiMTA-HUN-REN TTK "Momentum" Peptide-Based Vaccines Research Group, Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, Budapest, H-1117, Hungary.ORCID http://orcid.org/0000-0002-1352-2014
Szilvia BőszeHUN-REN ELTE Research Group of Peptide Chemistry, Hungarian Research Network, Eötvös Loránd University, Budapest, Hungary.
Judith MihályInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, H-1117, Hungary.
Bálint JezsóInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, H-1117, Hungary.ORCID http://orcid.org/0000-0002-1306-4797
Loránd RománszkiInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, H-1117, Hungary.ORCID http://orcid.org/0000-0002-6347-5228
Judit TóthInstitute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest, H-1117, Hungary.
Zoltán VargaInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, H-1117, Hungary.
István MándityInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, H-1117, Hungary.
Tünde JuhászInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, H-1117, Hungary.
Tamás Beke-SomfaiInstitute of Materials and Environmental Chemistry, HUN-REN Research Centre for Natural Sciences, Budapest, H-1117, Hungary. beke-somfai.tamas@ttk.hu.ORCID http://orcid.org/0000-0002-4788-3758
Eötvös Loránd University · HUInstitute of Materials and Environmental Chemistry · HUBudapest University of Technology and Economics · HUSemmelweis University · HU

Funding

EC | European Regional Development Fund (Europski Fond za Regionalni Razvoj) CZ.02.1.01/0.0/0.0/18_046/0015974
6 · The paper itself

Abstract

Developing unique mechanisms of action are essential to combat the growing issue of antimicrobial resistance. Supramolecular assemblies combining the improved biostability of non-natural compounds with the complex membrane-attacking mechanisms of natural peptides are promising alternatives to conventional antibiotics. However, for such compounds the direct visual insight on antibacterial action is still lacking. Here we employ a design strategy focusing on an inducible assembly mechanism and utilized electron microscopy (EM) to follow the formation of supramolecular structures of lysine-rich heterochiral β

Indexed as

Anti-Bacterial AgentsCell MembraneMolecular Dynamics SimulationEscherichia coliGram-Negative BacteriaLipopolysaccharidesMicrobial Sensitivity TestsMicroscopy, ElectronPeptidesAnti-Bacterial AgentsLipopolysaccharidesPeptides

Identifiers

PMID38654023
PMCPMC11039730
OpenAlexW4395038689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.