Evidence map›Paper›PMID 38653555›Full record

SynthesisRespiratory care2024

Positive Airway Pressure and Metabolic Markers in Children With Obstructive Sleep Apnea.

Christopher A Gerdung, Daniel B Ofosu, Sara Rodriguez-Lopez, Stefan Palkowski, Diana Keto-Lambert, Meng Lin, Maria L Castro-Codesal

Open access · greenAbstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Respiratory care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

  1. Article
  2. Canadian family physician Medecin de famille canadien
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Christopher A GerdungDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
Daniel B OfosuDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
Sara Rodriguez-LopezDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
Stefan PalkowskiDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
Diana Keto-LambertAlberta Strategy for Patient-Oriented Research Support Unit, Knowledge Translation Platform, University of Alberta, Edmonton, Alberta, Canada.
Meng LinAlberta Strategy for Patient-Oriented Research Support Unit, Data and Research Services, Alberta Health Services, Edmonton, Alberta, Canada.
Maria L Castro-CodesalDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada Castroco@ualberta.ca.
University of Alberta · CAAlberta College · LVAlberta Health Services · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncreasing evidence suggests an association between childhood obstructive sleep apnea (OSA) and metabolic syndrome, with more research available on the potential impacts of positive airway pressure (PAP) on metabolic markers in children. The purpose of this systematic review is to provide a systematic synthesis of the evidence on the effect of PAP use on metabolic markers in children with OSA.

methodsA search strategy with terms for "OSA" and metabolic markers in pediatrics was run to systematically assess 5 databases until August 26, 2022. Two reviewers independently screened eligible articles, extracted data, and conducted quality appraisal. Meta-analysis was done using random-effects models. Body mass index (BMI), glycemic, lipid, cardiovascular, and other metabolic and inflammatory markers were reported.

resultsSixteen studies (

conclusionsAlthough evidence on effects of PAP on metabolic markers in children with OSA is encouraging, available literature is limited. Longitudinal studies are still required to further assess the long-term influence of PAP on metabolic and inflammatory markers, particularly in children with obesity.

Indexed as

BiomarkersMetabolic SyndromeSleep Apnea, ObstructiveAdolescentBlood GlucoseBlood PressureBody Mass IndexChildChild, PreschoolContinuous Positive Airway PressureFemaleHeart RateHumansLipidsMalePediatric ObesityBiomarkersBlood GlucoseLipidsbody mass indexchildmetabolic markersobstructive sleep apneapediatricspositive airway pressure

Identifiers

PMID38653555
PMCPMC11298216
OpenAlexW4395029469

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.