Evidence map›Paper›PMID 38653505›Full record

ArticleBMJ open gastroenterology2024

Increased rate of pancreatitis in gender diverse and transgender patients on hormone therapy: a case series study.

Alexander Podboy, Catherine Casey, Ross C D Buerlein, Daniel S Strand, Vanessa M Shami, Andrew Y Wang

Open access · goldAbstract read
In one paragraph

Article in BMJ open gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alexander PodboyDivision of Gastroenterology and Hepatology, University of Virginia, Charlottesville, Virginia, USA apodboy@virginia.edu.ORCID 0000-0001-9353-4965
Catherine CaseyDepartment of Family Medicine, Section of Transgender Services, Charlottesville, Virginia, USA.
Ross C D BuerleinDivision of Gastroenterology and Hepatology, University of Virginia, Charlottesville, Virginia, USA.
Daniel S StrandDivision of Gastroenterology and Hepatology, University of Virginia, Charlottesville, Virginia, USA.
Vanessa M ShamiDivision of Gastroenterology and Hepatology, University of Virginia, Charlottesville, Virginia, USA.
Andrew Y WangDivision of Gastroenterology and Hepatology, University of Virginia, Charlottesville, Virginia, USA.
University of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is limited data on the incidence of gastrointestinal-specific pathology in gender non-conforming (GNC) populations.

methodsRetrospective analysis of pancreatitis incidence rates in transgender and GNC persons exposed and not exposed to gender-affirming hormone therapy (GAHT).

results7 of the 1333 patients on hormone therapy had an incidence of pancreatitis. 0 of the 615 patients with no history of GAHT use developed pancreatitis. Representing a 6.96 (95% CI 2.76 to 848.78) for the development of pancreatitis in patients with exposure to GAHT therapy.

conclusionClinicians working with GNC individuals should be aware of this possible association.

Indexed as

PancreatitisTransgender PersonsAdultAgedFemaleHormone Replacement TherapyHumansIncidenceMaleMiddle AgedRetrospective StudiesACUTE PANCREATITISADVERSE DRUG REACTIONSPANCREAS

Identifiers

PMID38653505
PMCPMC11043760
OpenAlexW4395052209

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.