Evidence map›Paper›PMID 38653331›Full record

ArticleOpen biology2024

Optogenetically engineered calcium oscillations promote autophagy-mediated cell death via AMPK activation.

Yi-Shyun Lai, Meng-Ru Hsieh, Thi My Hang Nguyen, Ying-Chi Chen, Hsueh-Chun Wang, Wen-Tai Chiu

Abstract read
In one paragraph

Article in Open biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yi-Shyun LaiDepartment of Biomedical Engineering, National Cheng Kung University, Tainan 701, Taiwan.ORCID 0000-0002-9538-6705
Meng-Ru HsiehDepartment of Biomedical Engineering, National Cheng Kung University, Tainan 701, Taiwan.ORCID 0000-0002-0645-5220
Thi My Hang NguyenDepartment of Biomedical Engineering, National Cheng Kung University, Tainan 701, Taiwan.ORCID 0000-0002-5330-816X
Ying-Chi ChenDepartment of Chemistry, National Cheng Kung University, Tainan 701, Taiwan.ORCID 0000-0003-3711-0329
Hsueh-Chun WangDepartment of Biomedical Engineering, National Cheng Kung University, Tainan 701, Taiwan.ORCID 0009-0007-7229-7017
Wen-Tai ChiuDepartment of Biomedical Engineering, National Cheng Kung University, Tainan 701, Taiwan.ORCID 0000-0003-0310-0675

Funding

National Science and Technology Council of Taiwan
6 · The paper itself

Abstract

Autophagy is a double-edged sword for cells; it can lead to both cell survival and death. Calcium (Ca

Indexed as

AMP-Activated Protein KinasesAutophagyCalciumOptogeneticsCalcium SignalingEnzyme ActivationIonomycinThapsigarginAMP-Activated Protein KinasesCalciumIonomycinThapsigarginAMPKautophagycalciumcell deathoptogenetics

Identifiers

PMID38653331
PMCPMC11057470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.