Evidence map›Paper›PMID 38652750›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Organ-delimited gene regulatory networks provide high accuracy in candidate transcription factor selection across diverse processes.

Rajeev Ranjan, Sonali Srijan, Somaiah Balekuttira, Tina Agarwal, Melissa Ramey, Madison Dobbins, Rachel Kuhn, Xiaojin Wang, Karen Hudson, Ying Li and 1 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Inferring Gene Networks from High-Throughput Transcriptomes.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rajeev RanjanDepartment of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907.ORCID 0000-0002-1344-4044
Sonali SrijanDepartment of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907.
Somaiah BalekuttiraDepartment of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907.
Tina AgarwalDepartment of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907.
Melissa RameyDepartment of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907.
Madison DobbinsDepartment of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907.
Rachel KuhnDepartment of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907.
Xiaojin WangDepartment of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907.
Karen HudsonUnited States Department of Agriculture-Agricultural Research Service Crop Production and Pest Control Research Unit, West Lafayette, IN 47907.
Ying LiDepartment of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907.ORCID 0000-0002-5258-7355
Kranthi VaralaDepartment of Horticulture and Landscape Architecture, Purdue University, West Lafayette, IN 47907.ORCID 0000-0003-1051-6636

Funding

Department of Agriculture National Institute of Food and Agriculture 1013620U.S. Department of Energy (DOE) DE-SC0020399
6 · The paper itself

Abstract

Organ-specific gene expression datasets that include hundreds to thousands of experiments allow the reconstruction of organ-level gene regulatory networks (GRNs). However, creating such datasets is greatly hampered by the requirements of extensive and tedious manual curation. Here, we trained a supervised classification model that can accurately classify the organ-of-origin for a plant transcriptome. This K-Nearest Neighbor-based multiclass classifier was used to create organ-specific gene expression datasets for the leaf, root, shoot, flower, and seed in

Indexed as

ArabidopsisGene Expression Regulation, PlantGene Regulatory NetworksTranscription FactorsArabidopsis ProteinsGene Expression ProfilingOrgan SpecificitySeedsTranscriptomeArabidopsis ProteinsTranscription FactorsArabidopsisgene regulatory networkmachine learningmeta-analysisseed lipid biosynthesis

Identifiers

PMID38652750
PMCPMC11066984

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.