Evidence map›Paper›PMID 38652687›Full record

ReviewThe Plant cell2024

Protein degradation in auxin response.

Martijn de Roij, Jan Willem Borst, Dolf Weijers

Open access · hybridAbstract readReview
In one paragraph

Review in The Plant cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Towards an integrated molecular understanding of plant hormones.Journal of integrative plant biology · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Mechanisms of auxin action in plant growth and development.Nature reviews. Molecular cell biology · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. Focus on proteolysis.The Plant cell · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Martijn de RoijLaboratory of Biochemistry, Wageningen University, Wageningen 6708WE, The Netherlands.ORCID 0000-0002-4724-9650
Jan Willem BorstLaboratory of Biochemistry, Wageningen University, Wageningen 6708WE, The Netherlands.ORCID 0000-0001-8176-9302
Dolf WeijersLaboratory of Biochemistry, Wageningen University, Wageningen 6708WE, The Netherlands.ORCID 0000-0003-4378-141X
Wageningen University & Research · NL

Funding

Netherlands Organization for Scientific Research OCENW.M20.031
6 · The paper itself

Abstract

The signaling molecule auxin sits at the nexus of plant biology where it coordinates essentially all growth and developmental processes. Auxin molecules are transported throughout plant tissues and are capable of evoking highly specific physiological responses by inducing various molecular pathways. In many of these pathways, proteolysis plays a crucial role for correct physiological responses. This review provides a chronology of the discovery and characterization of the auxin receptor, which is a fascinating example of separate research trajectories ultimately converging on the discovery of a core auxin signaling hub that relies on degradation of a family of transcriptional inhibitor proteins-the Aux/IAAs. Beyond describing the "classical" proteolysis-driven auxin response system, we explore more recent examples of the interconnection of proteolytic systems, which target a range of other auxin signaling proteins, and auxin response. By highlighting these emerging concepts, we provide potential future directions to further investigate the role of protein degradation within the framework of auxin response.

Indexed as

Indoleacetic AcidsPlant ProteinsProteolysisGene Expression Regulation, PlantPlant Growth RegulatorsReceptors, Cell SurfaceSignal TransductionIndoleacetic AcidsPlant Growth RegulatorsPlant ProteinsReceptors, Cell Surface

Identifiers

PMID38652687
PMCPMC11371164
OpenAlexW4395029565

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.