Evidence map›Paper›PMID 38652207›Full record

ReviewMedical oncology (Northwood, London, England)2024

Anti-cancer potential of zerumbone in cancer and glioma: current trends and future perspectives.

Alborz Soroush, Siavash Pourhossein, Dorrin Hosseingholizadeh, Ahmed Hjazi, Reza Shahhosseini, Haniyeh Kavoosi, Nazgol Kermanshahi, Parisa Behnamrad, Nima Ghavamikia, Mehdi Dadashpour and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medical oncology (Northwood, London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 4 countries.

Alborz SoroushRamsay Pharmacy Group, Melbourne, VIC, 3004, Australia.
Siavash PourhosseinDepartment of Pharmacy, Eastern Mediterranean University, via Mersin 10, Famagusta, North Cyprus, Turkey.
Dorrin HosseingholizadehFaculty of Pharmacy, Iran University of Medical Sciences, Tehran, Iran.
Ahmed HjaziDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia.
Reza ShahhosseiniFaculty of Medicine, Istanbul Medipol University, Istanbul, Turkey.
Haniyeh KavoosiFaculty of Pharmacy, Kerman University of Medical Sciences, Kerman, Iran.
Nazgol KermanshahiFaculty of Pharmacy, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Parisa BehnamradDepartment of Pharmaceutics, Faculty of Pharmacy, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Nima GhavamikiaCardiology Department, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. nima.ghavami2017@gmail.com.
Mehdi DadashpourDepartment of Medical Biotechnology, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran. dadashpourmehdi1400@gmail.com.
Sepideh Karkon ShayanSchool of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.
Shahid Sadoughi University of Medical Sciences and Health Services · IREastern Mediterranean University · CYGonabad University of Medical Sciences · IRIran University of Medical Sciences · IRIstanbul Medipol University · TRKerman University of Medical Sciences · IRPrince Sattam Bin Abdulaziz University · SASemnan University of Medical Sciences · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant-derived immunomodulators and antitumor factors have appealed lots of attention from natural product scientists for their efficiency and safety and their important contribution to well-designed targeted drug action and delivery mechanisms. Zerumbone (ZER), the chief component of Zingiber zerumbet rhizomes, has been examined for its wide-spectrum in the treatment of multi-targeted diseases. The rhizomes have been used as food flavoring agents in numerous cuisines and in flora medication. Numerous in vivo and in vitro experiments have prepared confirmation of ZER as a potent immunomodulator as well as a potential anti-tumor agent. This review is an interesting compilation of all the important results of the research carried out to date to investigate the immunomodulatory and anticancer properties of ZER. The ultimate goal of this comprehensive review is to supply updated information and a crucial evaluation on ZER, including its chemistry and immunomodulating and antitumour properties, which may be of principal importance to supply a novel pathway for subsequent investigation to discover new agents to treat cancers and immune-related sickness. In addition, updated information on the toxicology of ZER has been summarized to support its safety profile.

Indexed as

GliomaNeoplasmsSesquiterpenesAnimalsAntineoplastic AgentsAntineoplastic Agents, PhytogenicHumansZingiberaceaeAntineoplastic AgentsAntineoplastic Agents, PhytogenicSesquiterpenesAnti-tumorGliomaImmunomodulatorsZerumbone

Identifiers

PMID38652207
OpenAlexW4395037444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.