Evidence map›Paper›PMID 38652142›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2024

Outcomes of stereoelectroencephalography following failed epilepsy surgery in children.

Georgia M Wong, Ashley McCray, Kara Hom, Saige Teti, Nathan T Cohen, William D Gaillard, Chima O Oluigbo

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Stereoelectroencephalography-guided radiofrequency thermocoagulation for secondary occipital lobe epilepsy in a child: a case report.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Georgia M WongDepartment of Neurological Surgery, Georgetown University School of Medicine, Washington, DC, USA. gw294@georgetown.edu.
Ashley McCrayDepartment of Neurosurgery, Children's National Hospital, Washington, DC, 20012, USA.
Kara HomDepartment of Neurology, George Washington University School of Medicine, Washington, DC, USA.
Saige TetiDepartment of Neurosurgery, Children's National Hospital, Washington, DC, 20012, USA.
Nathan T CohenDepartment of Neurology, George Washington University School of Medicine, Washington, DC, USA.
William D GaillardDepartment of Neurology, George Washington University School of Medicine, Washington, DC, USA.
Chima O OluigboDepartment of Neurosurgery, Children's National Hospital, Washington, DC, 20012, USA. COluigbo@childrensnational.org.
Children's National · USGeorge Washington University · USNeurological Surgery · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionStereoelectroencephalography (SEEG) is valuable for delineating the seizure onset zone (SOZ) in pharmacoresistant epilepsy when non-invasive presurgical techniques are inconclusive. Secondary epilepsy surgery after initial failure is challenging and there is limited research on SEEG following failed epilepsy surgery in children.

objectiveThe objective of this manuscript is to present the outcomes of children who underwent SEEG after failed epilepsy surgery.

methodsIn this single-institution retrospective study, demographics, previous surgery data, SEEG characteristics, management, and follow-up were analyzed for pediatric patients who underwent SEEG after unsuccessful epilepsy surgery between August 2016 and February 2023.

resultsFifty three patients underwent SEEG investigation during this period. Of this, 13 patients were identified who had unsuccessful initial epilepsy surgery (24%). Of these 13 patients, six patients (46%) experienced unsuccessful resective epilepsy surgery that targeted the temporal lobe, six patients (46%) underwent surgery involving the frontal lobe, and one patient (8%) had laser interstitial thermal therapy (LITT) of the right insula. SEEG in two thirds of patients (4/6) with initial failed temporal resections revealed expanded SOZ to include the insula. All 13 patients (100%) had a subsequent surgery after SEEG which was either LITT (54%) or surgical resection (46%). After the subsequent surgery, a favorable outcome (Engel class I/II) was achieved by eight patients (62%), while five patients experienced an unfavorable outcome (Engel class III/IV, 38%). Of the six patients with secondary surgical resection, four patients (67%) had favorable outcomes, while of the seven patients with LITT, two patients (29%) had favorable outcomes (Engel I/II). Average follow-up after the subsequent surgery was 37 months ±23 months.

conclusionSEEG following initial failed resective epilepsy surgery may help guide next steps at identifying residual epileptogenic cortex and is associated with favorable seizure control outcomes.

Indexed as

Drug Resistant EpilepsyElectroencephalographyAdolescentChildChild, PreschoolFemaleHumansMaleNeurosurgical ProceduresRetrospective StudiesStereotaxic TechniquesTreatment FailureTreatment OutcomeEpilepsy surgeryFailed surgeryPediatricsSeizures

Identifiers

PMID38652142
OpenAlexW4395049722

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.