Evidence map›Paper›PMID 38651970›Full record

ArticleACS applied materials & interfaces2024

Harnessing Bioluminescent Bacteria to Develop an Enzymatic-free Enzyme-linked immunosorbent assay for the Detection of Clinically Relevant Biomarkers.

Liming Hu, Marianna Rossetti, José Francisco Bergua, Claudio Parolo, Ruslan Álvarez-Diduk, Lourdes Rivas, Andrea Idili, Arben Merkoçi

Open access · hybridAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Liming HuNanobioelectronics & Biosensors Group, Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Bellaterra 08193, Barcelona, Spain.ORCID 0000-0002-8666-9287
Marianna RossettiNanobioelectronics & Biosensors Group, Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Bellaterra 08193, Barcelona, Spain.
José Francisco BerguaNanobioelectronics & Biosensors Group, Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Bellaterra 08193, Barcelona, Spain.ORCID 0000-0002-5969-193X
Claudio ParoloBarcelona Institute for Global Health (ISGlobal), Hospital Clínic-Universitat de Barcelona, Barcelona 08036, Spain.ORCID 0000-0001-9481-4408
Ruslan Álvarez-DidukNanobioelectronics & Biosensors Group, Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Bellaterra 08193, Barcelona, Spain.ORCID 0000-0002-9876-1574
Lourdes RivasNanobioelectronics & Biosensors Group, Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Bellaterra 08193, Barcelona, Spain.ORCID 0000-0002-1510-5927
Andrea IdiliDepartment of Chemical Sciences and Technologies, University of Rome Tor Vergata, Via della Ricerca Scientifica, Rome 00133, Italy.ORCID 0000-0002-6004-270X
Arben MerkoçiNanobioelectronics & Biosensors Group, Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Bellaterra 08193, Barcelona, Spain.ORCID 0000-0003-2486-8085
Institut Català de Nanociència i Nanotecnologia · ESBarcelona Institute for Global Health · ESInstitució Catalana de Recerca i Estudis Avançats · ESUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enzyme-linked immunosorbent assay (ELISA) is the gold standard technique for measuring protein biomarkers due to its high sensitivity, specificity, and throughput. Despite its success, continuous advancements in ELISA and immunoassay formats are crucial to meet evolving global challenges and to address new analytical needs in diverse applications. To expand the capabilities and applications of immunoassays, we introduce a novel ELISA-like assay that we call Bioluminescent-bacteria-linked immunosorbent assay (BBLISA). BBLISA is an enzyme-free assay that utilizes the inner filter effect between the bioluminescent bacteria

Indexed as

BiomarkersEnzyme-Linked Immunosorbent AssayGoldLuminescent MeasurementsMetal NanoparticlesAliivibrio fischeriCOVID-19HumansImmunoglobulin GIridiumSARS-CoV-2BiomarkersGoldImmunoglobulin GIridiumhomogeneous immunoassayhuman IgGinner filter effectnanomaterialsnanoparticlespoint-of-care diagnosticsSARS-CoV-2 nucleoprotein

Identifiers

PMID38651970
PMCPMC11194763
OpenAlexW4395037413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.