Evidence map›Paper›PMID 38651941›Full record

ArticleJournal of agricultural and food chemistry2024

Cranberry Polyphenols and Prevention against Urinary Tract Infections: New Findings Related to the Integrity and Functionality of Intestinal and Urinary Barriers.

Dolores González de Llano, Mikel Roldán, Diego Taladrid, Edgard Relaño de la Guía, M Victoria Moreno-Arribas, Begoña Bartolomé

Open access · hybridAbstract read
In one paragraph

Article in Journal of agricultural and food chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. UropathogenicAntibiotics (Basel, Switzerland) · 2026
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dolores González de LlanoInstitute of Food Science Research (CIAL), CSIC-UAM, C/Nicolás Cabrera 9, Madrid 28049, Spain.ORCID 0000-0001-8140-7045
Mikel RoldánInstitute of Food Science Research (CIAL), CSIC-UAM, C/Nicolás Cabrera 9, Madrid 28049, Spain.
Diego TaladridInstitute of Food Science Research (CIAL), CSIC-UAM, C/Nicolás Cabrera 9, Madrid 28049, Spain.
Edgard Relaño de la GuíaInstitute of Food Science Research (CIAL), CSIC-UAM, C/Nicolás Cabrera 9, Madrid 28049, Spain.
M Victoria Moreno-ArribasInstitute of Food Science Research (CIAL), CSIC-UAM, C/Nicolás Cabrera 9, Madrid 28049, Spain.ORCID 0000-0002-4136-595X
Begoña BartoloméInstitute of Food Science Research (CIAL), CSIC-UAM, C/Nicolás Cabrera 9, Madrid 28049, Spain.ORCID 0000-0002-4470-251X
Instituto de Investigación en Ciencias de la Alimentación · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work seeks to generate new knowledge about the mechanisms underlying the protective effects of cranberry against urinary tract infections (UTI). Using Caco-2 cells grown in Transwell inserts as an intestinal barrier model, we found that a cranberry-derived digestive fluid (containing 135 ± 5 mg of phenolic compounds/L) increased transepithelial electrical resistance with respect to control (ΔTEER = 54.5 Ω cm

Indexed as

Plant ExtractsPolyphenolsUrinary Tract InfectionsVaccinium macrocarponCaco-2 CellsEscherichia coli InfectionsFruitHumansIntestinal MucosaIntestinesOccludinTight JunctionsUropathogenic Escherichia coliZonula Occludens-1 ProteinOccludinPlant ExtractsPolyphenolsZonula Occludens-1 Proteincranberryintestinal barrierparacellular permeabilityphenolic metabolitesTEERtight junctionsurinary barrierurinary tract infections (UTI)

Identifiers

PMID38651941
PMCPMC11082924
OpenAlexW4395049778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.