Evidence map›Paper›PMID 38651449›Full record

ReviewHematology reports2024

Ophthalmic Manifestations in Patients with Blood Malignancies.

Costanza Rossi, Alessandro Buizza, Giuseppe Alessio, Massimiliano Borselli, Andrea Taloni, Adriano Carnevali, Giovanna Carnovale Scalzo, Andrea Lucisano, Vincenzo Scorcia, Giuseppe Giannaccare

Open access · goldAbstract readReview
In one paragraph

Review in Hematology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Macular Hemorrhage as the First Manifestation of Leukemia.Diagnostics (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Costanza RossiDepartment of Ophthalmology, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0003-1094-7540
Alessandro BuizzaDepartment of Biomedical Sciences, Humanitas University, via Rita Levi Montalcini 4, 20072 Milan, Italy.ORCID 0009-0008-5764-1964
Giuseppe AlessioDepartment of Ophthalmology, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.
Massimiliano BorselliDepartment of Ophthalmology, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0001-5262-9765
Andrea TaloniDepartment of Ophthalmology, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.
Adriano CarnevaliDepartment of Ophthalmology, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.
Giovanna Carnovale ScalzoDepartment of Ophthalmology, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.
Andrea LucisanoDepartment of Ophthalmology, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0003-1382-0828
Vincenzo ScorciaDepartment of Ophthalmology, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0001-6826-7957
Giuseppe GiannaccareEye Clinic, Department of Surgical Sciences, University of Cagliari, 09123 Cagliari, Italy.ORCID 0000-0003-2617-0289
Magna Graecia University · ITHumanitas University · ITUniversity of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ocular complications can occur in up to 90% of patients with blood malignancies. Such complications range from direct infiltration to local hemostatic imbalance and treatment-related toxicity. This narrative review is based on a systematic computerized search of the literature conducted until January 2024 and examines the common ocular complications associated with blood cancers. Ocular complications from primary disease include mass effects from ocular adnexal lymphomas and intraocular lymphomas, with B-cell lymphomas accounting for 95% of primary ocular presentations. Secondary disease involvement from systemic hematological malignancies can lead to a wide range of ocular manifestations, such as leukemic retinopathy. Furthermore, toxicity from antineoplastic therapies and ocular graft versus host disease (oGVHD) after hematopoietic stem cell transplantation present additional risks to ocular health. In conclusion, ocular complications in blood cancer patients are an integral part of patient management, requiring regular ophthalmic evaluations and close collaboration between oncologists and ophthalmologists. Advances in therapy and an increased focus on early symptom recognition are essential for preserving vision and enhancing patient quality of life.

Indexed as

antineoplastic therapy toxicityhematological malignanciesleukemic retinopathyocular complicationsocular graft versus host disease

Identifiers

PMID38651449
PMCPMC11036248
OpenAlexW4393253331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.