Evidence map›Paper›PMID 38651445›Full record

ArticleVision (Basel, Switzerland)2024

Features Associated with Visible Lamina Cribrosa Pores in Individuals of African Ancestry with Glaucoma: Primary Open-Angle African Ancestry Glaucoma Genetics (POAAGG) Study.

Jalin A Jordan, Ebenezer Daniel, Yineng Chen, Rebecca J Salowe, Yan Zhu, Eydie Miller-Ellis, Victoria Addis, Prithvi S Sankar, Di Zhu, Eli J Smith and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vision (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Jalin A JordanDepartment of Ophthalmology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Ebenezer DanielDepartment of Ophthalmology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Yineng ChenDepartment of Ophthalmology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Rebecca J SaloweDepartment of Ophthalmology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Yan ZhuDepartment of Ophthalmology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Eydie Miller-EllisDepartment of Ophthalmology, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-9710-9990
Victoria AddisDepartment of Ophthalmology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Prithvi S SankarDepartment of Ophthalmology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Di ZhuDepartment of Ophthalmology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Eli J SmithDepartment of Ophthalmology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Roy LeeDepartment of Ophthalmology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Gui-Shuang YingDepartment of Ophthalmology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Joan M O'BrienDepartment of Ophthalmology, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-4109-2928
University of Pennsylvania · US

Funding

Scientific TransparencyP30EY001583 · NEI · UNIVERSITY OF PENNSYLVANIA · PI Qi N Cui · 1985 to 2026
$19.5M
Primary Open Angle African-American Glaucoma Genetics Study RenewalR01EY023557 · NEI · UNIVERSITY OF PENNSYLVANIA · PI O'BRIEN, JOAN M · 2014 to 2025
$18.1M
NEI NIH HHS #1RO1EY023557NEI NIH HHS P30 EY001583NEI NIH HHS R01 EY023557
6 · The paper itself

Abstract

There are scarce data regarding the rate of the occurrence of primary open-angle glaucoma (POAG) and visible lamina cribrosa pores (LCPs) in the eyes of individuals with African ancestry; the potential impact of these features on disease burden remains unknown. We recruited subjects with POAG to the Primary Open-Angle African American Glaucoma Genetics (POAAGG) study. Through regression models, we evaluated the association between the presence of LCPs and various phenotypic features. In a multivariable analysis of 1187 glaucomatous eyes, LCPs were found to be more likely to be present in eyes with cup-to-disc ratios (CDR) of ≥0.9 (adjusted risk ratio (aRR) 1.11, 95%CI: 1.04-1.19,

Indexed as

African ancestrylamina cribrosa poresprimary open-angle glaucomastereo optic disc images

Identifiers

PMID38651445
PMCPMC11036295
OpenAlexW4394920090

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.