Evidence map›Paper›PMID 38651442›Full record

ArticleVision (Basel, Switzerland)2024

Short-Term Morpho-Functional Changes before and after Strabismus Surgery in Children Using Structural Optical Coherence Tomography: A Pilot Study.

Pasquale Viggiano, Marida Gaudiomonte, Ugo Procoli, Luisa Micelli Ferrari, Enrico Borrelli, Giacomo Boscia, Andrea Ferrara, Fabio De Vitis, Gemma Scalise, Valeria Albano and 2 more

Open access · goldAbstract read
In one paragraph

Article in Vision (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Pasquale ViggianoDepartment of Translational Biomedicine Neuroscience, University of Bari "Aldo Moro", 70125 Bari, Italy.ORCID 0000-0002-0323-967X
Marida GaudiomonteDepartment of Translational Biomedicine Neuroscience, University of Bari "Aldo Moro", 70125 Bari, Italy.
Ugo ProcoliDepartment of Translational Biomedicine Neuroscience, University of Bari "Aldo Moro", 70125 Bari, Italy.
Luisa Micelli FerrariDepartment of Translational Biomedicine Neuroscience, University of Bari "Aldo Moro", 70125 Bari, Italy.
Enrico BorrelliDepartment of Surgical Sciences, University of Turin, 10124 Turin, Italy.ORCID 0000-0003-2815-5031
Giacomo BosciaDepartment of Translational Biomedicine Neuroscience, University of Bari "Aldo Moro", 70125 Bari, Italy.ORCID 0000-0002-8768-899X
Andrea FerraraDepartment of Translational Biomedicine Neuroscience, University of Bari "Aldo Moro", 70125 Bari, Italy.
Fabio De VitisDepartment of Translational Biomedicine Neuroscience, University of Bari "Aldo Moro", 70125 Bari, Italy.
Gemma ScaliseDepartment of Translational Biomedicine Neuroscience, University of Bari "Aldo Moro", 70125 Bari, Italy.
Valeria AlbanoDepartment of Translational Biomedicine Neuroscience, University of Bari "Aldo Moro", 70125 Bari, Italy.ORCID 0000-0002-6193-3299
Giovanni AlessioDepartment of Translational Biomedicine Neuroscience, University of Bari "Aldo Moro", 70125 Bari, Italy.
Francesco BosciaDepartment of Translational Biomedicine Neuroscience, University of Bari "Aldo Moro", 70125 Bari, Italy.
University of Bari Aldo Moro · ITCTO Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the immediate alterations in the thickness of the macular ganglion cell-inner plexiform layer (mGCIPL), peripapillary retinal nerve fiber layer (RNFL), inner retinal layer (IRL), and outer retinal layer (ORL) using spectral domain optical coherence tomography (SD-OCT) subsequent to strabismus surgery in pediatric patients diagnosed with horizontal esotropia.

methodsTwenty-eight eyes from twenty-one child patients who had undergone uncomplicated horizontal rectus muscle surgery due to strabismus were included. Measurements of RNFL, mGCL-IPL, IRL, and ORL using structural OCT were conducted both before the surgery and one month after the surgical procedure. Importantly, a control group comprising 14 healthy eyes, matched for age and significant refractive error (<3.00 diopters), was included in the current analysis.

resultsOur analysis indicated no significant disparity before and after surgery in terms of best-corrected visual acuity (BCVA), RNFL, IRL, and ORL. Conversely, concerning the macular ganglion cell layer-inner plexiform layer analysis, a substantial increase in mGCL-IPL was observed following the surgical intervention. The mean mGCL-IPL measured 60.8 ± 9.2 μm at baseline and 66.1 ± 13.2 μm one month after the surgery (

conclusionsFollowing strabismus surgery, our observations pointed towards a thickening of the mGCL-IPL layer, which is likely attributable to transient local inflammation. Additionally, we identified a significant differentiation in the mGCL-IPL complex between the pediatric patient group with strabismus and the control group.

Indexed as

macular ganglion cell–inner plexiform layerOCTstrabismus

Identifiers

PMID38651442
PMCPMC11036279
OpenAlexW4394843294

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.