Evidence map›Paper›PMID 38651091›Full record

ArticleERJ open research2024

Severe asthma care trajectories: the French RAMSES cohort.

Jeanne-Marie Perotin, Lisa Gauquelin, Nicolas Just, Gilles Devouassoux, Cécile Chenivesse, Arnaud Bourdin, Gilles Garcia, Christel Saint Raymond, Amel Boudjemaa, Philippe Bonniaud and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ERJ open research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Jeanne-Marie PerotinDepartment of Respiratory Diseases, University Hospital of Reims, Reims, France.
Lisa GauquelinAP-HP, Centre de Pharmacoépidémiologie (Cephepi), Paris, France.
Nicolas JustRespiratory Diseases Department, Victor Provo Hospital, Roubaix, France.
Gilles DevouassouxCRISALIS/F-CRIN INSERM Network, France.
Cécile ChenivesseUniversity of Reims Champagne-Ardenne, Inserm UMR-S 1250, SFR Cap-Santé, Reims, France.
Arnaud BourdinUniversité de Montpellier, PhyMedExp, INSERM, CNRS, Montpellier, France.ORCID https://orcid.org/0000-0002-4645-5209
Gilles GarciaService de Pneumologie, Hôpital Privé d'Antony, Antony, France.
Christel Saint RaymondService de Pneumologie, CHU Grenoble Alpes, Grenoble, France.ORCID https://orcid.org/0000-0003-0958-4041
Amel BoudjemaaService de Pneumologie, CHI de Créteil, Créteil, France.
Philippe BonniaudUniversity of Reims Champagne-Ardenne, Inserm UMR-S 1250, SFR Cap-Santé, Reims, France.
Pascal ChanezAix-Marseille Université, INSERM, INRAE, C2VN, Marseille, France.ORCID https://orcid.org/0000-0003-4059-0917
Cindy BarnigUniversity of Reims Champagne-Ardenne, Inserm UMR-S 1250, SFR Cap-Santé, Reims, France.ORCID https://orcid.org/0000-0001-8890-3236
Antoine BeurnierDepartment of Physiology - Functional Explorations, bi-site Hôpital Bicêtre (Le Kremlin-Bicêtre) and Ambroise Paré (Boulogne-Billancourt), DMU 5 Thorinno, AP-HP, Université Paris-Saclay, INSERM UMR_S 999, Paris, France.ORCID https://orcid.org/0000-0002-0481-3266
Cyril MaurerGroupe Hospitalier Intercommunal Le Raincy-Montfermeil, Montfermeil, France.
Nathalie FreymondRespiratory Diseases and Thoracic Oncology Department, Lyon Sud Hospital, Hospices Civils de Lyon, Lyon, France.
Toufik DidiService de Pneumologie, CH Annecy Genevois, Metz-Tessy, France.
Colas TcherakianDepartment of Respiratory Diseases, Foch Hospital, Suresnes, France.
Maud RussierPneumo-allergology Department, Orléans Regional Hospital Center, Orléans, France.
Mélanie DrucbertDepartment of Respiratory Disease, University Hospital of Amiens, Amiens, France.
Sylvie GuilloSorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique - IPLESP, AP-HP, Hôpital Pitié Salpêtrière, Cephepi, Paris, France.
Candice EstellatSorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique - IPLESP, AP-HP, Hôpital Pitié Salpêtrière, Cephepi, Paris, France.
Camille TailléDepartment of Respiratory Diseases, Reference Center for Rare Pulmonary Diseases, Bichat Hospital, AP-HP, Paris, France.ORCID https://orcid.org/0000-0001-9768-5728

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The French RAMSES study is an observational prospective multicentre real-life cohort including severe asthmatic subjects. The objective of the study was to compare the characteristics of patients, in terms of phenotype and asthma care trajectories, between those managed by tertiary referral centres (TRCs) or secondary care centres (SCCs). Methods: Patients were prospectively recruited and enrolled for a 5-year follow-up. Patients' characteristics were analysed at inclusion and compared between TRCs and SCCs. Results: 52 centres (24 TRCs and 28 SCCs) included 2046 patients: 1502 (73.4%) were included by a TRC and 544 (26.6%) by a SCC. Patients were mainly women (62%), 53±15 years old, 67% with Asthma Control Test <20; at inclusion, 14% received oral corticosteroids (OCS) and 66% biologics. Compared with the SCC group, the TRC group had more frequent comorbidities and lower blood eosinophil counts (262 Conclusions: Phenotypes and care trajectories differed in the RAMSES cohort between SCCs and TRCs, probably related to different levels of asthma severity and differences in medical resources and practices among centres. This highlights the need for standardisation of severe asthma care.

Identifiers

PMID38651091
PMCPMC11033728

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.