Evidence map›Paper›PMID 38651004›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2024

CDPNet: a radiomic feature learning method with epigenetic application to estimating MGMT promoter methylation status in glioblastoma.

Jun Guo, Fanyang Yu, MacLean P Nasrallah, Christos Davatzikos

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Diagnostic Accuracy of Artificial Intelligence for Predicting MGMT Promoter Methylation in Glioblastoma Using MR Imaging: A Systematic Review.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
    Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jun GuoCenter for Biomedical Image Computing and Analytics, University of Pennsylvania, 3700 Hamilton Walk, Philadelphia, PA, 19104, USA.
Fanyang YuCenter for Biomedical Image Computing and Analytics, University of Pennsylvania, 3700 Hamilton Walk, Philadelphia, PA, 19104, USA.
MacLean P NasrallahCenter for Biomedical Image Computing and Analytics, University of Pennsylvania, 3700 Hamilton Walk, Philadelphia, PA, 19104, USA.
Christos DavatzikosCenter for Biomedical Image Computing and Analytics, University of Pennsylvania, 3700 Hamilton Walk, Philadelphia, PA, 19104, USA.

Funding

Statistical atlases of brain tumor MRI:do imaging phenotypes predict progression?R01NS042645 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2002 to 2024
$8.7M
Generalizable quantitative imaging and machine learning signatures in glioblastoma, for precision diagnostics and personalized treatment: the ReSPOND consortiumR01CA269948 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Christos Davatzikos · 2022 to 2026
$3.2M
Cancer imaging phenomics software suite: application to brain and breast cancerU24CA189523 · NCI · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS, KONTOS, DESPINA · 2015 to 2019
$3.2M
The Federated Tumor Segmentation (FeTS) platform: An intuitive tool facilitating secure multi-institutional collaborationU01CA242871 · NCI · UNIVERSITY OF PENNSYLVANIA · PI BAKAS, SPYRIDON · 2019 to 2021
$1.1M
NCI NIH HHS R01 CA269948NCI NIH HHS U01 CA242871NCI NIH HHS U24 CA189523NINDS NIH HHS R01 NS042645
6 · The paper itself

Abstract

Radiomics has been widely recognized for its effectiveness in decoding tumor phenotypes through the extraction of quantitative imaging features. However, the robustness of radiomic methods to estimate clinically relevant biomarkers non-invasively remains largely untested. In this study, we propose Cascaded Data Processing Network (CDPNet), a radiomic feature learning method to predict tumor molecular status from medical images. We apply CDPNet to an epigenetic case, specifically targeting the estimation of

Indexed as

classificationfeature learningGlioblastomaMGMT promoter methylationMRI scans

Identifiers

PMID38651004
PMCPMC11034757

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.