Evidence map›Paper›PMID 38650989›Full record

ArticleiScience2024

Bacterial symbionts in oral niche use type VI secretion nanomachinery for fitness increase against pathobionts.

Jan Oscarsson, Kai Bao, Akiko Shiratsuchi, Jonas Grossmann, Witold Wolski, Kyaw Min Aung, Mark Lindholm, Anders Johansson, Ferdousi Rahman Mowsumi, Sun Nyunt Wai and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
3.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Jan OscarssonOral Microbiology, Department of Odontology, Umeå University, Umeå, Sweden.
Kai BaoDivision of Oral Health and Periodontology, Department of Dental Medicine, Karolinska Institutet, Alfred Nobels Allé 8, 14104 Huddinge, Stockholm, Sweden.
Akiko ShiratsuchiDepartment of Liberal Arts and Sciences, Graduate School of Medicine, Sapporo Medical University, Sapporo, Hokkaido 060-8556, Japan.
Jonas GrossmannFunctional Genomics Center Zurich, ETH Zürich and University of Zürich, Zürich, Switzerland.
Witold WolskiFunctional Genomics Center Zurich, ETH Zürich and University of Zürich, Zürich, Switzerland.
Kyaw Min AungDepartment of Molecular Biology and the Umeå Centre for Microbial Research (UCMR), and the Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, 90187 Umeå, Sweden.
Mark LindholmOral Microbiology, Department of Odontology, Umeå University, Umeå, Sweden.
Anders JohanssonOral Microbiology, Department of Odontology, Umeå University, Umeå, Sweden.
Ferdousi Rahman MowsumiOral Microbiology, Department of Odontology, Umeå University, Umeå, Sweden.
Sun Nyunt WaiDepartment of Molecular Biology and the Umeå Centre for Microbial Research (UCMR), and the Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, 90187 Umeå, Sweden.
Georgios N BelibasakisDivision of Oral Health and Periodontology, Department of Dental Medicine, Karolinska Institutet, Alfred Nobels Allé 8, 14104 Huddinge, Stockholm, Sweden.
Nagihan BostanciDivision of Oral Health and Periodontology, Department of Dental Medicine, Karolinska Institutet, Alfred Nobels Allé 8, 14104 Huddinge, Stockholm, Sweden.
Umeå University · SEKarolinska Institutet · SESIB Swiss Institute of Bioinformatics · CHSapporo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbial ecosystems experience spatial and nutrient restrictions leading to the coevolution of cooperation and competition among cohabiting species. To increase their fitness for survival, bacteria exploit machinery to antagonizing rival species upon close contact. As such, the bacterial type VI secretion system (T6SS) nanomachinery, typically expressed by pathobionts, can transport proteins directly into eukaryotic or prokaryotic cells, consequently killing cohabiting competitors. Here, we demonstrate for the first time that oral symbiont

Indexed as

BacteriologyMicrobial floraMicrobial interactions

Identifiers

PMID38650989
PMCPMC11033201
OpenAlexW4393321625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.