Evidence map›Paper›PMID 38650980›Full record

ArticleiScience2024

The trogocytosis of neutrophils on initial transplanted tumor in mice.

Mengru Zhu, Shengnan Wang, Kuo Qu, Feiyu Lu, Mengyuan Kou, Yunpeng Yao, Tong Zhu, Yongli Yu, Liying Wang, Chaoying Yan

Open access · goldAbstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trogocytosis in cancer immunity and cellular immunotherapy: mechanisms, therapeutic challenges, and translational opportunities.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Mengru ZhuDepartment of Neonatology and Institute of Pediatrics, Children's Medical Center, First Hospital of Jilin University, Jilin University, Changchun, Jilin 130021, People's Republic of China.
Shengnan WangDepartment of Molecular Biology, College of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, People's Republic of China.
Kuo QuDepartment of Immunology, College of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, People's Republic of China.
Feiyu LuDepartment of Molecular Biology, College of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, People's Republic of China.
Mengyuan KouDepartment of Immunology, College of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, People's Republic of China.
Yunpeng YaoDepartment of Molecular Biology, College of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, People's Republic of China.
Tong ZhuDepartment of Neonatology and Institute of Pediatrics, Children's Medical Center, First Hospital of Jilin University, Jilin University, Changchun, Jilin 130021, People's Republic of China.
Yongli YuDepartment of Immunology, College of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, People's Republic of China.
Liying WangDepartment of Neonatology and Institute of Pediatrics, Children's Medical Center, First Hospital of Jilin University, Jilin University, Changchun, Jilin 130021, People's Republic of China.
Chaoying YanDepartment of Neonatology and Institute of Pediatrics, Children's Medical Center, First Hospital of Jilin University, Jilin University, Changchun, Jilin 130021, People's Republic of China.
Jilin Medical University · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of neutrophils in tumor initiation stage is rarely reported because of the lack of suitable models. We found that neutrophils recruited in early tumor nodules induced by subcutaneous inoculation of B16 melanoma cells were able to attack tumor cells by trogocytosis. The anti-tumor immunotherapy like peritoneal injection with TLR9 agonist CpG oligodeoxynucleotide combined with transforming growth factor β2 inhibitor TIO3 could increase the trogocytic neutrophils in the nodules, as well as CD8

Indexed as

Biological sciencesCancerCell biology

Identifiers

PMID38650980
PMCPMC11033691
OpenAlexW4393951492

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.